{"id":"W3083468887","doi":"10.1083/jcb.202006196","title":"Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration","year":2020,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"RIKEN; Japan Society for the Promotion of Science; Philomathia Foundation; Chan Zuckerberg Initiative; Japan Science and Technology Agency; Uehara Memorial Foundation; Takeda Science Foundation","keywords":"Lamellipodium; Adherens junction; Cell biology; Cell migration; Actin; Motility; Biology; Chemistry; Cell; Cadherin; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001363567,0.0002827435,0.000210394,0.0002173257,0.0005773181,0.0004518879,0.0002311833,0.0003446943,0.001260764],"category_scores_gemma":[0.0001133702,0.0001616546,0.0002196369,0.0001239407,0.0002188885,0.0003141189,0.0003426245,0.0007672354,0.0005418535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004838486,"about_ca_system_score_gemma":0.0003801307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136669,"about_ca_topic_score_gemma":0.001642566,"domain_scores_codex":[0.9998602,0.00001786993,0.000007564356,0.00003042969,0.00004695966,0.00003706909],"domain_scores_gemma":[0.9999118,0.000005594478,0.00002020458,0.000007548905,0.00002065151,0.00003422908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003048176,0.00001307745,0.0001875345,0.0000194909,0.000001585685,0.00005728144,0.00001342546,0.00003391147,0.9985594,0.0003428922,0.00006761166,0.0006733233],"study_design_scores_gemma":[0.0000192717,0.00007108038,0.03058699,0.00001462014,0.00001846487,0.0002554684,0.0001313969,0.00416758,0.9571208,0.0003278925,0.00727379,0.00001258353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789228,0.005470001,0.01016569,0.0002677838,0.0001183624,0.00004740266,0.0002236662,0.0002648405,0.004519474],"genre_scores_gemma":[0.994756,0.0007675395,0.001619116,0.00006287964,0.00001116022,0.00002090434,0.0001435249,0.00001614509,0.002602768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260764,"threshold_uncertainty_score":0.004217625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399083997200273,"score_gpt":0.2301824329296747,"score_spread":0.216191592957672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}