{"id":"W3083745584","doi":"10.1002/cam4.3390","title":"Associations between safety, tolerability, and toxicity and the reporting of health‐related quality of life in phase III randomized trials in common solid tumors","year":2020,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Cancer survivorship and care","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Discontinuation; Tolerability; Adverse effect; Quality of life (healthcare); Internal medicine; Randomized controlled trial; Clinical trial; Odds ratio","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.03852724,0.0001509157,0.007448295,0.00009736116,0.00004378079,0.000002964492,0.00006666846,0.0000930527,0.00006189908],"category_scores_gemma":[0.03795882,0.00009550955,0.0001555175,0.0005132403,0.0006183668,0.000038059,0.00005489325,0.0003557865,4.073783e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001388708,"about_ca_system_score_gemma":0.0004162769,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05414134,"about_ca_topic_score_gemma":0.006568314,"domain_scores_codex":[0.9869312,0.002976359,0.009204419,0.0002854935,0.0004024067,0.0002000921],"domain_scores_gemma":[0.9878951,0.005488976,0.006053541,0.0002181444,0.0001495904,0.0001946698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1072992,0.0002258312,0.7920811,0.001639605,0.0004751496,0.00000828579,0.07129785,0.00002718183,0.001012166,0.0004661336,0.0002410295,0.02522638],"study_design_scores_gemma":[0.6374577,0.0004699729,0.3528154,0.001838344,0.0004133839,0.00000214831,0.004202912,0.0005187192,0.0005499898,0.001549766,0.0000275624,0.000154054],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9246918,0.01097939,0.00008203695,0.06218501,0.0001077611,0.001634372,0.00008540167,0.00001325987,0.0002209962],"genre_scores_gemma":[0.997134,0.001068236,0.00000810706,0.001518781,0.0001495426,0.00004925544,0.00005423263,0.00001013886,0.000007702037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5301585,"threshold_uncertainty_score":0.9900385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1670134740089452,"score_gpt":0.4502560741822744,"score_spread":0.2832426001733292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}