{"id":"W3083785934","doi":"10.3389/fimmu.2020.01909","title":"Toward a Membrane-Centric Biology","year":2020,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Signal transduction; Cell biology; Receptor; Cell surface receptor; Cell signaling; Cell membrane; Systems biology; Lipid bilayer; Membrane protein; Cell; Computational biology; Membrane; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00384221,0.0009841148,0.001688618,0.001498138,0.001265327,0.004934456,0.002682693,0.004221659,0.002703201],"category_scores_gemma":[0.001857653,0.0006544018,0.0009509954,0.0006203052,0.01028431,0.01314941,0.004452282,0.008023174,0.002683472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003530944,"about_ca_system_score_gemma":0.00249755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006632304,"about_ca_topic_score_gemma":0.0004522219,"domain_scores_codex":[0.9987317,0.0002953037,0.00004929348,0.0003995901,0.0003914135,0.0001326366],"domain_scores_gemma":[0.9985313,0.0003547982,0.0001192958,0.0003228325,0.0003815501,0.0002901897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00001860663,0.00003027742,0.0001960734,0.0002319263,0.00001582041,0.00007224303,0.0002687646,0.001280703,0.007023095,0.97692,0.003495658,0.01044691],"study_design_scores_gemma":[0.00001336433,0.00005590032,0.0002362079,0.0001169063,0.00001363775,0.0001613164,0.0002134422,0.00763336,0.003902144,0.879595,0.1080251,0.00003368192],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.03096065,0.09937396,0.66855,0.1143177,0.005174738,0.0001202463,0.0004514769,0.001388203,0.07966296],"genre_scores_gemma":[0.4699182,0.1050467,0.3540429,0.02081326,0.007899838,0.0005144193,0.0007505958,0.0007258572,0.04028818],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004934456,"threshold_uncertainty_score":0.02561897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171435980069161,"score_gpt":0.2299362888252814,"score_spread":0.2182219290245898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}