{"id":"W3083912737","doi":"10.1007/s11626-020-00490-1","title":"Pharmacological and nutritional modulation of autophagy in a rainbow trout (Oncorhynchus mykiss) gill cell line, RTgill-W1","year":2020,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Huntsman Marine Science Centre; Mowi (Canada); University of Guelph","funders":"Ontario Veterinary College, University of Guelph; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Autophagy; BECN1; Rainbow trout; Western blot; Biology; Cell biology; Downregulation and upregulation; Immunoglobulin light chain; Autophagy-related protein 13; Immunofluorescence; Microtubule; Blot; Molecular biology; Gene; Signal transduction; Biochemistry; Immunology; Antibody; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001532315,0.0001637372,0.0002519116,0.0002155421,0.0003286942,0.0002839223,0.0001723229,0.0002676683,0.001077838],"category_scores_gemma":[0.00007488771,0.0001067959,0.0003066316,0.0001867669,0.0002358422,0.0002134862,0.0001588057,0.0005307925,0.0002287042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005667752,"about_ca_system_score_gemma":0.0004812516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005157005,"about_ca_topic_score_gemma":0.01792443,"domain_scores_codex":[0.9998767,0.00001343362,0.00002178866,0.00002646977,0.00002665088,0.00003477505],"domain_scores_gemma":[0.9999515,0.000009218727,0.000009636593,0.000007085305,0.00000821438,0.00001431599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001702312,0.0000436209,0.0002302716,0.00003292182,0.000004513175,0.00004071572,0.00002668006,0.00004559906,0.9988813,0.0001094764,0.00007815791,0.0003364445],"study_design_scores_gemma":[0.00006630214,0.001142997,0.01919462,0.00001265178,0.00005416261,0.0002384205,0.00021699,0.0008311133,0.9735038,0.00007121414,0.004653634,0.00001420974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965178,0.0006248844,0.0003841227,0.0001299295,0.00003463285,0.00001694341,0.0007471644,0.00004003544,0.001504398],"genre_scores_gemma":[0.9901083,0.0006789935,0.001365576,0.0001241372,0.000008506428,0.00005534281,0.001553992,0.00001906154,0.006086064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005157005,"threshold_uncertainty_score":0.01025397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02515384860051059,"score_gpt":0.2767711939187283,"score_spread":0.2516173453182178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}