{"id":"W3083912737","doi":"10.1007/s11626-020-00490-1","title":"Pharmacological and nutritional modulation of autophagy in a rainbow trout (Oncorhynchus mykiss) gill cell line, RTgill-W1","year":2020,"lang":"en","type":"article","venue":"In Vitro Cellular & Developmental Biology - Animal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Huntsman Marine Science Centre; Mowi (Canada); University of Guelph","funders":"Ontario Veterinary College, University of Guelph; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs","keywords":"Autophagy; BECN1; Rainbow trout; Western blot; Biology; Cell biology; Downregulation and upregulation; Immunoglobulin light chain; Autophagy-related protein 13; Immunofluorescence; Microtubule; Blot; Molecular biology; Gene; Signal transduction; Biochemistry; Immunology; Antibody; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001686944,0.0002430782,0.0005139246,0.0001787578,0.00004268395,0.000005890571,0.0001098618,0.0002573954,0.0002641143],"category_scores_gemma":[0.00003688109,0.0002258086,0.0000898189,0.0002863327,0.0002097581,0.00007574225,0.00008882963,0.0003053415,0.00001852239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001145414,"about_ca_system_score_gemma":0.0001557536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002480737,"about_ca_topic_score_gemma":0.000001704663,"domain_scores_codex":[0.9983733,0.0001049036,0.0005648115,0.0004688958,0.0001500813,0.000338059],"domain_scores_gemma":[0.9995372,0.00008048114,0.0001189689,0.00006418701,0.00003739127,0.0001617599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002811804,0.0005576333,0.02797358,0.00006621616,0.00005068498,0.0003073062,0.0003442494,0.00000728767,0.9663097,0.0001295895,0.00002691798,0.001415075],"study_design_scores_gemma":[0.006651399,0.0006310105,0.1517428,0.00002613928,0.00003056975,0.00002973551,0.0001383793,0.003939801,0.8358609,0.000293277,0.0004337219,0.0002222967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971374,0.00106927,0.00009740915,0.0005786578,0.0000423722,0.0004967554,0.00005722361,0.00004058046,0.0004802871],"genre_scores_gemma":[0.9944157,0.0001118822,0.003395785,0.001498417,0.0001308124,0.00004712207,0.0003601077,0.00001855021,0.00002161821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1304488,"threshold_uncertainty_score":0.9208208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02515384860051059,"score_gpt":0.2767711939187283,"score_spread":0.2516173453182178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}