{"id":"W3083968962","doi":"10.1016/j.vetpar.2020.109240","title":"Contrasting patterns of isotype-1 β-tubulin allelic diversity in Haemonchus contortus and Haemonchus placei in the southern USA are consistent with a model of localised emergence of benzimidazole resistance","year":2020,"lang":"en","type":"article","venue":"Veterinary Parasitology","topic":"Helminth infection and control","field":"Veterinary","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Haemonchus contortus; Biology; Haplotype; Benzimidazole; Genetic diversity; Anthelmintic; Nematode; Livestock; Allele; Genetics; Veterinary medicine; Population; Zoology; Gene; Ecology; Demography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002502851,0.0002074457,0.0006798649,0.0000961558,0.00005849716,0.000004542579,0.0002608905,0.0001305094,0.00005258475],"category_scores_gemma":[0.00008609828,0.0001717969,0.00007161909,0.0001713609,0.0002673629,0.00006846026,0.0001443649,0.0002192088,0.000002293302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001847249,"about_ca_system_score_gemma":0.00004943323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009732521,"about_ca_topic_score_gemma":0.002533205,"domain_scores_codex":[0.9981914,0.0003676326,0.0006248134,0.0003476272,0.0001971953,0.0002714013],"domain_scores_gemma":[0.9988937,0.0002452662,0.00043941,0.0002567442,0.00008988444,0.00007501782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008808362,0.0002646812,0.9543036,0.0004546645,0.00009670151,0.0007379473,0.01228971,0.001810236,0.02066136,0.0001334264,0.00003252726,0.0004068207],"study_design_scores_gemma":[0.009374528,0.005501376,0.9003603,0.0005233792,0.0001414424,0.0003563929,0.01661411,0.06540931,0.0009636663,0.00007991039,0.0001011847,0.0005743837],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967219,0.0002760054,0.001615738,0.0004490225,0.00003822061,0.0004214511,0.0001645369,0.00001292373,0.0003002392],"genre_scores_gemma":[0.9995228,0.00003215557,0.0001286875,0.000250191,0.00001377278,0.00002675821,0.000004529647,0.00001173227,0.000009383562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06359907,"threshold_uncertainty_score":0.7005673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1148843066212104,"score_gpt":0.3150391613760462,"score_spread":0.2001548547548359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}