{"id":"W3084058862","doi":"10.1186/s13059-020-02081-5","title":"The Tug1 lncRNA locus is essential for male fertility","year":2020,"lang":"en","type":"article","venue":"Genome biology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; Broad Institute; National Institutes of Health; Harvard University; Howard Hughes Medical Institute","keywords":"Biology; Locus (genetics); Gene; Genetics; Genome; Repressor; Long non-coding RNA; Small nucleolar RNA; Computational biology; Gene expression; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119464,0.0004432347,0.0002909357,0.0004130563,0.000207547,0.0002416071,0.0003073598,0.0003865127,0.002145221],"category_scores_gemma":[0.0002014718,0.000118045,0.0002949706,0.0001921035,0.0003595011,0.0001019769,0.0003267786,0.0004064152,0.0005007106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002303824,"about_ca_system_score_gemma":0.0003095997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003195772,"about_ca_topic_score_gemma":0.0007100402,"domain_scores_codex":[0.9998747,0.00001393528,0.00001164798,0.00003707317,0.00003547018,0.00002704634],"domain_scores_gemma":[0.99968,0.0000676563,0.0001379912,0.00002151133,0.00001307957,0.00007968547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008789528,0.00001202307,0.001565759,0.00005028423,0.000007942081,0.0004586153,0.00002217378,0.0001026354,0.9953252,0.0001451344,0.00006381705,0.002158421],"study_design_scores_gemma":[0.000028639,0.0002463903,0.05382269,0.00003725347,0.00005582279,0.003339789,0.00006745199,0.001504862,0.9342741,0.0002325688,0.006373182,0.00001724229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892664,0.00229726,0.005382924,0.0001580462,0.00004040442,0.000021901,0.001227992,0.0005230875,0.001082004],"genre_scores_gemma":[0.9952587,0.0004787211,0.002111733,0.00005064576,0.00001344585,0.00002177499,0.0009205023,0.00006190791,0.001082637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002145221,"threshold_uncertainty_score":0.007176518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644022937503221,"score_gpt":0.2864184962229379,"score_spread":0.2699782668479057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}