{"id":"W3084176537","doi":"10.1111/all.14582","title":"Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma","year":2020,"lang":"en","type":"review","venue":"Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Allergy Therapeutics; Mylan; Sanofi","keywords":"Medicine; Atopic dermatitis; Asthma; Allergy; Allergen immunotherapy; Precision medicine; Biomarker; Personalized medicine; Endotype; Intensive care medicine; Disease; Immunology; Microbiome; Omalizumab; Immunoglobulin E; Allergen; Bioinformatics; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025463,0.0002396845,0.001085305,0.0002017362,0.00003348567,0.00001264011,0.00003916283,0.0001883861,0.00002422053],"category_scores_gemma":[0.0002019104,0.0001902797,0.0001589014,0.0001734126,0.0000840641,0.00004542366,0.00002957456,0.00008328949,4.614936e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000303202,"about_ca_system_score_gemma":0.0001382154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002818975,"about_ca_topic_score_gemma":0.0000152038,"domain_scores_codex":[0.9987718,0.0001232801,0.0004788834,0.0003535133,0.0001376597,0.0001348936],"domain_scores_gemma":[0.9990215,0.0004680128,0.0001967321,0.000142456,0.00005305327,0.0001182364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004904385,0.00009342456,0.0004073883,0.00340854,0.0006210115,0.00004581104,0.0001395022,2.52744e-7,0.000001666044,0.0001356772,0.001381011,0.9932753],"study_design_scores_gemma":[0.001379815,0.0005857362,0.005835983,0.004515652,0.0001320993,0.00005374527,0.00004003623,0.0001142406,0.000001333366,0.00004356118,0.9871639,0.0001338786],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001739193,0.9963747,0.00002120792,0.0002967974,0.00008153162,0.001122433,0.0002642057,0.00002406314,0.00007590764],"genre_scores_gemma":[0.0008448423,0.998025,0.0001567734,0.00008617379,0.0001154226,0.0002413512,0.000434857,0.00004273426,0.00005283648],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9931414,"threshold_uncertainty_score":0.7759381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05163794610650688,"score_gpt":0.3144401439123394,"score_spread":0.2628021978058325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}