{"id":"W3084198342","doi":"10.1093/biolre/ioaa159","title":"ORP9 knockdown delays the maturation of junction-related endocytic structures in the testis and leads to impaired sperm release†","year":2020,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene knockdown; Cell biology; Endocytic cycle; Endocytosis; Biology; Endoplasmic reticulum; Sertoli cell; Internalization; Sperm; Spermatogenesis; Cell; Endocrinology; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216746,0.0004245194,0.0003700078,0.0003191464,0.0002138674,0.0003490209,0.0003359397,0.0003980493,0.003910278],"category_scores_gemma":[0.00008127443,0.000236053,0.0003841329,0.0001810366,0.0003069958,0.0003415945,0.0002416801,0.0008609155,0.0007818651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003676715,"about_ca_system_score_gemma":0.0003386372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001818722,"about_ca_topic_score_gemma":0.003340644,"domain_scores_codex":[0.9997973,0.0000162752,0.00002480526,0.00006185307,0.00005732149,0.00004244411],"domain_scores_gemma":[0.9998062,0.00001648923,0.00005630016,0.00001376429,0.00001705054,0.00009025529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001145736,0.00002402522,0.0001731248,0.00006120642,0.00001128729,0.0001045397,0.00000929152,0.00004708648,0.998427,0.0001029051,0.0001050729,0.0008198589],"study_design_scores_gemma":[0.00002809228,0.0003450784,0.01088587,0.00001152707,0.00005405795,0.0003374275,0.0000502297,0.001062083,0.9829494,0.00005280444,0.004214619,0.000008886554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980165,0.003554775,0.007833105,0.0003071892,0.000211822,0.00008443539,0.003592339,0.0005080596,0.003743278],"genre_scores_gemma":[0.97975,0.001962682,0.003002187,0.0001542536,0.00001877476,0.00006764752,0.001944944,0.0001213577,0.01297813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003910278,"threshold_uncertainty_score":0.01308119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02204240005633479,"score_gpt":0.2576091264585321,"score_spread":0.2355667264021973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}