{"id":"W3084198342","doi":"10.1093/biolre/ioaa159","title":"ORP9 knockdown delays the maturation of junction-related endocytic structures in the testis and leads to impaired sperm release†","year":2020,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene knockdown; Cell biology; Endocytic cycle; Endocytosis; Biology; Endoplasmic reticulum; Sertoli cell; Internalization; Sperm; Spermatogenesis; Cell; Endocrinology; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002584603,0.00008787798,0.0001757739,0.00006698914,0.00004882739,0.000003713868,0.00004769324,0.00008590686,0.00003231609],"category_scores_gemma":[0.001458081,0.00004906451,0.00003808836,0.0003746509,0.000139503,0.00003790648,0.00001639917,0.0001452364,0.000004616279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002122322,"about_ca_system_score_gemma":0.00003665151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001524405,"about_ca_topic_score_gemma":0.00001269588,"domain_scores_codex":[0.9991584,0.0001073711,0.0002673617,0.0002877987,0.00008886125,0.00009021084],"domain_scores_gemma":[0.9994034,0.0000789364,0.0001203713,0.0002687847,0.00009894287,0.0000296185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00150213,0.0001148573,0.1875668,0.0001600164,0.0001118411,0.000008673926,0.004052169,0.000467343,0.7392561,0.002149933,0.001987237,0.06262283],"study_design_scores_gemma":[0.000984839,0.001630547,0.9467461,0.00003764101,0.0001700624,0.0006632049,0.0007516313,0.00062018,0.04541302,0.001004974,0.001880186,0.00009757814],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875374,0.001208136,0.0001632243,0.01019818,0.0002868045,0.0004901823,0.00000231549,0.00002679132,0.00008697462],"genre_scores_gemma":[0.9991189,0.00007471052,0.0002723091,0.000220502,0.0002362847,0.00001130998,0.00003606583,0.000006399404,0.00002357736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7591793,"threshold_uncertainty_score":0.2000792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02204240005633479,"score_gpt":0.2576091264585321,"score_spread":0.2355667264021973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}