{"id":"W3084255724","doi":"10.1016/j.tins.2020.08.004","title":"Circuit-Based Biomarkers for Mood and Anxiety Disorders","year":2020,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Memory and Neural Mechanisms","field":"Neuroscience","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Mental Health; Pew Charitable Trusts; Human Frontier Science Program; Esther A. and Joseph Klingenstein Fund; Canadian Institutes of Health Research; International Mental Health Research Organization; McKnight Endowment Fund for Neuroscience","keywords":"Neuroscience; Anxiety; Psychology; Mood; Mood disorders; Biomarker; Brain activity and meditation; Clinical psychology; Electroencephalography; Psychiatry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001064745,0.001401185,0.002037355,0.001325676,0.0001707164,0.001259454,0.001436183,0.001554917,0.003216376],"category_scores_gemma":[0.001728916,0.0002855566,0.000688489,0.001050764,0.0007609559,0.001440649,0.0007165314,0.00231909,0.002051197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006484125,"about_ca_system_score_gemma":0.001040812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008649526,"about_ca_topic_score_gemma":0.001948757,"domain_scores_codex":[0.9997416,0.00005500258,0.00002772528,0.0000673688,0.00008406914,0.00002426994],"domain_scores_gemma":[0.9994045,0.0003262253,0.00008087266,0.00002320008,0.0001290162,0.0000360665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001774987,0.00007976654,0.0006044985,0.007615308,0.0002261221,0.0001631076,0.00002278273,0.0004504182,0.003006533,0.005178328,0.03042249,0.9520531],"study_design_scores_gemma":[0.0001432819,0.0004702627,0.004615513,0.006604107,0.0007614155,0.001910191,0.00008758603,0.0008877119,0.00326745,0.02226194,0.9588937,0.00009695241],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001393486,0.9972638,0.0006885967,0.0005944935,0.0003998782,0.000008831807,0.00006050146,0.00001939292,0.0008251497],"genre_scores_gemma":[0.002306132,0.9936141,0.001134081,0.0008696662,0.0009253382,0.00002770124,0.0001310063,0.000004377939,0.0009876221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003216376,"threshold_uncertainty_score":0.01075989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2100128385238332,"score_gpt":0.3904395682745459,"score_spread":0.1804267297507127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}