{"id":"W3084266909","doi":"10.1128/msphere.00594-20","title":"Binding of Leishmania infantum Lipophosphoglycan to the Midgut Is Not Sufficient To Define Vector Competence in <i>Lutzomyia longipalpis</i> Sand Flies","year":2020,"lang":"en","type":"article","venue":"mSphere","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Leishmania infantum; Midgut; Biology; Lipophosphoglycan; Leishmania; Visceral leishmaniasis; Microbiology; Mutant; Parasite hosting; Leishmaniasis; Immunology; Ecology; Leishmania donovani; Larva; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008153635,0.0001314922,0.0001095115,0.0001371519,0.00008921593,0.0001781955,0.00008426182,0.0001507845,0.0006629078],"category_scores_gemma":[0.0001082865,0.00008728965,0.00008467512,0.00004802211,0.0001364655,0.0001356096,0.0001580145,0.0002192208,0.000162433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001550819,"about_ca_system_score_gemma":0.0001047476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001024431,"about_ca_topic_score_gemma":0.002160147,"domain_scores_codex":[0.9999428,0.00001122381,0.000005294995,0.000009219711,0.0000123083,0.00001925903],"domain_scores_gemma":[0.9999001,0.00002227082,0.00003086199,0.000006175995,0.00001123681,0.00002937069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003098468,0.000007209483,0.00142991,0.00001484438,0.000001714821,0.0000201756,0.00002364054,0.000009766559,0.9979532,0.00002819033,0.000006374129,0.0004741217],"study_design_scores_gemma":[0.00001405608,0.0009115198,0.2580687,0.00001585578,0.00001980509,0.0005353224,0.0003064293,0.0006666777,0.7377259,0.00009177793,0.001635012,0.000008941345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989899,0.000235127,0.0002535262,0.00001557554,0.000001412947,0.000005932835,0.00005009715,0.000006394689,0.0004418821],"genre_scores_gemma":[0.9988585,0.0001296846,0.0005090997,0.00002250536,0.000001383748,0.00000596013,0.0001529606,0.000002991105,0.0003170311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024431,"threshold_uncertainty_score":0.002217591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03555635032794572,"score_gpt":0.2849193157093111,"score_spread":0.2493629653813654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}