{"id":"W3084303996","doi":"10.1161/hyp.76.suppl_1.mp26","title":"Abstract MP26: Endothelial-derived Microvesicles From Andean Highlanders With Excessive Erythrocytosis Induce A Deleterious Cardiomyocyte Phenotype","year":2020,"lang":"en","type":"article","venue":"Hypertension","topic":"Cardiovascular Health and Risk Factors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of Alberta; University of Windsor","funders":"","keywords":"Enos; Endothelial dysfunction; Medicine; Cardiac fibrosis; Internal medicine; Asymmetric dimethylarginine; Cardiac function curve; Endocrinology; Heart failure; Microvesicle; CD31; Microvesicles; Endothelium; Fibrosis; Nitric oxide; Nitric oxide synthase; Biology; Angiogenesis; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001194213,0.0002542037,0.0001716123,0.0002286318,0.0002726566,0.0002190344,0.0001025017,0.000169079,0.001952188],"category_scores_gemma":[0.000193928,0.00009005229,0.000179598,0.0001246702,0.0002327376,0.0001059599,0.0003615433,0.0002198446,0.0002533418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001269241,"about_ca_system_score_gemma":0.00009387158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001684771,"about_ca_topic_score_gemma":0.002145107,"domain_scores_codex":[0.999917,0.0000122228,0.000006859039,0.00002080494,0.00001526296,0.00002772752],"domain_scores_gemma":[0.999909,0.000008308479,0.0000282414,0.00001090491,0.00001587315,0.00002763949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0017427,0.0001697682,0.04176212,0.0001104397,0.00006447853,0.00124705,0.0004542335,0.00003787238,0.9504878,0.00003704895,0.0001738743,0.003712719],"study_design_scores_gemma":[0.0001200848,0.002499255,0.9040109,0.00002937441,0.0001039076,0.006821177,0.001410417,0.0002348516,0.0821501,0.00006969104,0.002536678,0.00001346146],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995463,0.00008080611,0.00006766506,0.00001095546,0.000001946355,0.000007302741,0.00008400446,0.000002684658,0.0001983167],"genre_scores_gemma":[0.9985254,0.0001096906,0.0001723905,0.00002933775,0.000005749673,0.00001631706,0.0003456242,0.000003699827,0.000791835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001952188,"threshold_uncertainty_score":0.006530762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03089784064066149,"score_gpt":0.2289566353729828,"score_spread":0.1980587947323213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}