{"id":"W3084364727","doi":"10.1158/2326-6074.tumimm18-b85","title":"Abstract B85: Anticancer efficacy of a novel immune-stimulating oncolytic virus: VG161 in gastrointestinal cancers","year":2020,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada)","funders":"","keywords":"Oncolytic virus; Immune system; ELISPOT; Cancer; Cancer research; Virotherapy; Immunotherapy; Herpes simplex virus; Immunology; Immunogenic cell death; Medicine; Cancer immunotherapy; Virus; Biology; T cell; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001060137,0.0002686818,0.0004625969,0.0002488463,0.0001318623,0.00002796005,0.0009087503,0.0002038013,0.0003634966],"category_scores_gemma":[0.001015541,0.0002798031,0.0001457181,0.0008770652,0.000967505,0.00001295675,0.0004543655,0.001097637,0.00003251289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003589166,"about_ca_system_score_gemma":0.00214252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001859797,"about_ca_topic_score_gemma":0.0009040936,"domain_scores_codex":[0.9967061,0.0002628514,0.0006223283,0.0007629775,0.0005392682,0.001106536],"domain_scores_gemma":[0.9983391,0.0002452399,0.0001519219,0.0006140532,0.0004714506,0.0001782149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009279641,0.0001990275,0.006979156,0.00008667156,0.0001324396,0.00002311269,0.0002611543,0.005345732,0.9710303,0.00001499435,0.0001708044,0.006476947],"study_design_scores_gemma":[0.009178912,0.00901814,0.05230289,0.0006119012,0.00001592719,0.00003203974,0.0006014975,0.00337157,0.9223575,0.00001869188,0.001942299,0.0005486472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913929,0.005943228,0.0001130949,0.001040343,0.00006921912,0.0006437122,0.00007126178,0.00001805674,0.0007082435],"genre_scores_gemma":[0.9978772,0.0009816047,0.0003726228,0.000171926,0.0002641481,0.0001331851,0.00003678007,0.00006636632,0.00009618393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04867284,"threshold_uncertainty_score":0.9999654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09335631015325443,"score_gpt":0.4112996011107808,"score_spread":0.3179432909575264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}