{"id":"W3084368441","doi":"10.1038/s41386-020-00859-6","title":"Habenular TCF7L2 links nicotine addiction to diabetes: the broad significance","year":2020,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Nicotine; Addiction; Psychology; TCF7L2; Diabetes mellitus; Neuroscience; Psychiatry; Medicine; Pharmacology; Endocrinology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002465465,0.0004411251,0.0003620326,0.0003651578,0.0002991967,0.00100651,0.0004942848,0.0008568317,0.003791675],"category_scores_gemma":[0.0002619197,0.0001905125,0.0003458915,0.000248583,0.0007200656,0.0004535224,0.0004682385,0.001044609,0.0006777259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006497639,"about_ca_system_score_gemma":0.0005404964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003319991,"about_ca_topic_score_gemma":0.005504192,"domain_scores_codex":[0.9998536,0.00001801104,0.000006144924,0.00003827823,0.00003643767,0.00004743847],"domain_scores_gemma":[0.99983,0.00001987791,0.00004713363,0.00002278653,0.00002830609,0.00005192443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00207095,0.0001437537,0.03861995,0.0002713072,0.0002940911,0.001974876,0.0001604451,0.0008594885,0.8976788,0.009502145,0.003601282,0.04482296],"study_design_scores_gemma":[0.0003772008,0.0008098575,0.4847528,0.0002543017,0.0005893569,0.004986926,0.001410819,0.009240198,0.4210176,0.01283654,0.06355681,0.0001675492],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9569167,0.0204166,0.006630927,0.00419563,0.0003506262,0.0000338509,0.001842584,0.0003097729,0.009303411],"genre_scores_gemma":[0.9871717,0.004012282,0.0009365004,0.000473546,0.00007391732,0.00002294427,0.0007671478,0.00004899074,0.00649303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003791675,"threshold_uncertainty_score":0.01268446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01304770979775593,"score_gpt":0.2604308431221319,"score_spread":0.2473831333243759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}