{"id":"W3084884859","doi":"10.1016/j.cbd.2020.100744","title":"Dicamba elevates concentrations of S-adenosyl methionine but does not induce oxidative stress or alter DNA methylation in rainbow trout (Oncorhynchus mykiss) hepatocytes","year":2020,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part D Genomics and Proteomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Lethbridge","funders":"Canadian Foundation for Pharmacy; Natural Sciences and Engineering Research Council of Canada","keywords":"Dicamba; Oxidative stress; Rainbow trout; Lipid peroxidation; Glutathione; Methylation; Chemistry; Toxicity; DNA methylation; Biology; Biochemistry; DNA; Ecology; Gene; Enzyme; Fishery; Gene expression; Fish <Actinopterygii>","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725739,0.000363285,0.0004043138,0.0003436271,0.0002979477,0.0002826664,0.0003211006,0.0003110814,0.002322716],"category_scores_gemma":[0.0001461717,0.0002604833,0.0003352894,0.0001969887,0.0005028697,0.0003588136,0.0003080269,0.000656482,0.0004097096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006621444,"about_ca_system_score_gemma":0.0005825665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007654461,"about_ca_topic_score_gemma":0.01486166,"domain_scores_codex":[0.9998235,0.00001826494,0.00002298118,0.00005444391,0.00002760057,0.00005312033],"domain_scores_gemma":[0.999821,0.00002433249,0.00003981415,0.00002956807,0.00002433349,0.00006103051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005536086,0.00002056527,0.0002389321,0.00002008846,0.000007193469,0.00005055885,0.00002183811,0.00002798422,0.9985988,0.0000705526,0.00007936974,0.0003105783],"study_design_scores_gemma":[0.00004930878,0.0005292469,0.009923579,0.000003781163,0.00003262622,0.0001033008,0.0001082722,0.000358406,0.987361,0.00004990981,0.001469964,0.00001064498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957784,0.0007305864,0.0006913125,0.0002100559,0.0001138302,0.00002011484,0.0008588174,0.0001035415,0.001493234],"genre_scores_gemma":[0.9931717,0.0003037065,0.0009346213,0.0001007927,0.00001986974,0.00003730632,0.0008588681,0.00002813224,0.004545072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007654461,"threshold_uncertainty_score":0.01521981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03793416595237916,"score_gpt":0.2899058504472401,"score_spread":0.251971684494861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}