{"id":"W3084908975","doi":"10.1007/s00223-020-00753-9","title":"Effects of Reduced Connexin43 Function on Mandibular Morphology and Osteogenesis in Mutant Mouse Models of Oculodentodigital Dysplasia","year":2020,"lang":"en","type":"article","venue":"Calcified Tissue International","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Endochondral ossification; Intramembranous ossification; Mutant; Ossification; Mandible (arthropod mouthpart); Phenotype; Cartilage; Biology; Anatomy; Wild type; Dysplasia; Dental alveolus; Osteogenesis imperfecta; Pathology; Cell biology; Genetics; Gene; Medicine; Dentistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004646518,0.0009231243,0.0007364257,0.001980828,0.0006445404,0.0005930756,0.0005858942,0.001337491,0.002687657],"category_scores_gemma":[0.0004346098,0.0007156937,0.0005346034,0.0005576262,0.001357922,0.0004726642,0.0005522712,0.001092291,0.0003122533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007765623,"about_ca_system_score_gemma":0.0006362167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003738582,"about_ca_topic_score_gemma":0.007554906,"domain_scores_codex":[0.9992898,0.0001220387,0.000105509,0.0001144109,0.000231739,0.0001365458],"domain_scores_gemma":[0.9993181,0.0001231327,0.0002124326,0.00005961967,0.00004135693,0.000245413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005907526,0.00009295393,0.0002377545,0.00003448466,0.00001326007,0.0002767348,0.00004122993,0.0001714124,0.9976699,0.0003096104,0.00003631232,0.0005256588],"study_design_scores_gemma":[0.0001135656,0.0006180099,0.006044199,0.0000176362,0.0000863029,0.0009535516,0.0001800253,0.001284572,0.9889075,0.0002037291,0.001569182,0.00002182516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967332,0.000734791,0.0008369019,0.0001263354,0.0000380894,0.00002916502,0.0004522226,0.00006853922,0.0009807964],"genre_scores_gemma":[0.9910419,0.000779612,0.00198797,0.00007610401,0.00001192214,0.00009177095,0.0003920711,0.0001316684,0.005486967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003738582,"threshold_uncertainty_score":0.008991122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01308467430875676,"score_gpt":0.2437200132990819,"score_spread":0.2306353389903251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}