{"id":"W3085296521","doi":"10.1667/rade-20-00008.1","title":"Effects of Gadolinium MRI Contrast Agents on DNA Damage and Cell Survival when Used in Combination with Radiation","year":2020,"lang":"en","type":"article","venue":"Radiation Research","topic":"Lanthanide and Transition Metal Complexes","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Physical Laboratory; Medical Research Council; Queen's University; Queen's University Belfast","keywords":"Gadolinium; DU145; Radiosensitivity; Clonogenic assay; DNA damage; Cell culture; Nuclear medicine; Cell; Chemistry; Magnetic resonance imaging; Pathology; Medicine; Radiation therapy; Biology; Cancer cell; Cancer; DNA; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003461981,0.0004036258,0.0004519452,0.0002787359,0.0001648819,0.0003038325,0.0002053217,0.0003421044,0.001013364],"category_scores_gemma":[0.0004353269,0.0002045684,0.0002707792,0.0002243689,0.0002031316,0.0002293759,0.0002283941,0.0004956819,0.0002763172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001987326,"about_ca_system_score_gemma":0.0002101593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000786382,"about_ca_topic_score_gemma":0.001244008,"domain_scores_codex":[0.9996426,0.000119107,0.00002501357,0.00006950626,0.0000834898,0.00006022601],"domain_scores_gemma":[0.9996474,0.0001295653,0.00006059305,0.00003023065,0.00008437669,0.00004792162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000616113,0.0001011295,0.0004167318,0.0001764532,0.00003218157,0.00007620288,0.00009171349,0.0001390507,0.9943414,0.00003434608,0.0001070335,0.003867708],"study_design_scores_gemma":[0.00001666687,0.002741764,0.003964581,0.00001812804,0.0000552639,0.0001951421,0.00006518315,0.0004119936,0.9903725,0.00002260227,0.002126587,0.000009595443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857414,0.0105085,0.001390657,0.0001214301,0.00008055381,0.00004084691,0.000170201,0.00007463286,0.001871662],"genre_scores_gemma":[0.9869854,0.004557373,0.003403602,0.0001209956,0.00004105391,0.00008259352,0.0004362731,0.00004843989,0.004324222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001013364,"threshold_uncertainty_score":0.003390074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04828482735975939,"score_gpt":0.3096563937585219,"score_spread":0.2613715663987625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}