{"id":"W3085296521","doi":"10.1667/rade-20-00008.1","title":"Effects of Gadolinium MRI Contrast Agents on DNA Damage and Cell Survival when Used in Combination with Radiation","year":2020,"lang":"en","type":"article","venue":"Radiation Research","topic":"Lanthanide and Transition Metal Complexes","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Physical Laboratory; Medical Research Council; Queen's University; Queen's University Belfast","keywords":"Gadolinium; DU145; Radiosensitivity; Clonogenic assay; DNA damage; Cell culture; Nuclear medicine; Cell; Chemistry; Magnetic resonance imaging; Pathology; Medicine; Radiation therapy; Biology; Cancer cell; Cancer; DNA; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008475989,0.00008573353,0.0001835475,0.0001768459,0.00007823535,0.00006717885,0.0001118836,0.00004951143,0.0001059987],"category_scores_gemma":[0.0001253769,0.00007418292,0.00001713427,0.0003033168,0.00007884973,0.0002196015,0.00001996041,0.0001431402,0.00004607324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000370952,"about_ca_system_score_gemma":0.00005577737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000130189,"about_ca_topic_score_gemma":0.00003373024,"domain_scores_codex":[0.9981641,0.0005535112,0.0002038895,0.0002494978,0.0006237464,0.0002052462],"domain_scores_gemma":[0.9990072,0.0006131172,0.00007380707,0.00009902328,0.0001041768,0.000102629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006056311,0.0003008264,0.01008699,0.0004254354,0.000009218197,0.00002111728,0.003199144,0.0003406047,0.9818338,0.002181732,0.0004117285,0.0005837753],"study_design_scores_gemma":[0.004036425,0.0007913852,0.2217341,0.00004063689,0.000008541436,3.119409e-7,0.0001340366,0.004568654,0.7679752,0.0004336929,0.0001694534,0.0001075973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970829,0.00004545791,0.0006206199,0.001250997,0.00006116644,0.0005733611,0.00002034075,0.00002062561,0.000324462],"genre_scores_gemma":[0.9995668,0.00004975187,0.0001324215,0.0001189339,0.00004359838,0.00002152685,0.00003202943,0.00001122067,0.00002373653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2138587,"threshold_uncertainty_score":0.3025092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04828482735975939,"score_gpt":0.3096563937585219,"score_spread":0.2613715663987625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}