{"id":"W3085578913","doi":"10.2337/dc19-2267","title":"Dual-Hormone Closed-Loop System Using a Liquid Stable Glucagon Formulation Versus Insulin-Only Closed-Loop System Compared With a Predictive Low Glucose Suspend System: An Open-Label, Outpatient, Single-Center, Crossover, Randomized Controlled Trial","year":2020,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes Management and Research","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Steno Diabetes Center Copenhagen; Juvenile Diabetes Research Foundation United Kingdom","keywords":"Medicine; Artificial pancreas; Glucagon; Crossover study; Hypoglycemia; Interquartile range; Insulin; Endocrinology; Hormone; Internal medicine; Diabetes mellitus; Closed loop; Type 2 diabetes; Type 1 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002190229,0.001724097,0.005125691,0.0005442268,0.000484568,0.00134986,0.001276271,0.002096036,0.004758302],"category_scores_gemma":[0.002515422,0.0007648567,0.001922923,0.0005505201,0.001660499,0.001388982,0.0004757913,0.002669454,0.0006022706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007519122,"about_ca_system_score_gemma":0.00124057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006928691,"about_ca_topic_score_gemma":0.0009350788,"domain_scores_codex":[0.9986614,0.000655442,0.0001278092,0.0002870706,0.0001360157,0.0001321727],"domain_scores_gemma":[0.9979941,0.000827997,0.0004534242,0.0001372913,0.000139876,0.0004473449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9828832,0.009501944,0.000161399,0.0003478024,0.0003772637,0.00001095144,0.00001631865,0.00009241197,0.00113565,0.00002848687,0.00008896449,0.005355694],"study_design_scores_gemma":[0.8676871,0.1303701,0.0006185849,0.00002076196,0.0003621348,0.000009401929,0.0000127526,0.0003638405,0.0003881698,0.00004076824,0.0001176582,0.000008719228],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990728,0.002675643,0.001011458,0.0002429981,0.000630179,0.003612333,0.0003494371,0.00009678736,0.0006530915],"genre_scores_gemma":[0.9868773,0.001782834,0.003565116,0.0005603204,0.0008052018,0.004772629,0.000379727,0.00002276036,0.001234076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005125691,"threshold_uncertainty_score":0.01591808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04831284612686508,"score_gpt":0.2961604056341818,"score_spread":0.2478475595073167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}