{"id":"W3085713224","doi":"10.1097/aln.0000000000003547","title":"Genomic Screening for Malignant Hyperthermia Susceptibility","year":2020,"lang":"en","type":"review","venue":"Anesthesiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health","keywords":"Medicine; Malignant hyperthermia; Hyperthermia; Intensive care medicine; Computational biology; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002724825,0.0004781338,0.003408089,0.0001002972,0.0001293035,0.00000560584,0.0001713434,0.0007769669,0.00008463888],"category_scores_gemma":[0.0002187054,0.0003463856,0.001447971,0.0001384037,0.0002053544,0.00001616488,0.00006296022,0.0006440504,0.0002562352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007359035,"about_ca_system_score_gemma":0.000448894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000837467,"about_ca_topic_score_gemma":0.000001616424,"domain_scores_codex":[0.9976313,0.0003893184,0.0005719681,0.0008213812,0.00006458603,0.0005214707],"domain_scores_gemma":[0.9983107,0.000669449,0.0002460708,0.0005534396,0.00005618966,0.0001640954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002431498,0.00002879692,0.00009490917,0.005331489,0.0003725202,0.0007986219,0.00002121931,5.179156e-7,0.00009477834,0.0001689224,0.0008356954,0.9920094],"study_design_scores_gemma":[0.0003698441,0.001126531,0.0005690951,0.001124713,0.001565285,0.0039471,0.000007222661,0.000005389421,0.000005178777,0.0001457008,0.9908168,0.0003171487],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002727978,0.9950245,0.00003750372,0.000126272,0.0001329746,0.00171886,0.00002840425,0.0001052198,0.00009831112],"genre_scores_gemma":[0.0004655583,0.9953694,0.0009023436,0.0009511711,0.001235595,0.0002943362,0.0004410484,0.0001009208,0.0002396058],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9916922,"threshold_uncertainty_score":0.9998988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05446790029799779,"score_gpt":0.3252092568756161,"score_spread":0.2707413565776183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}