{"id":"W3085724501","doi":"10.1111/hae.14131","title":"Gene therapy to cure haemophilia: Is robust scientific inquiry the missing factor?","year":2020,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Hemophilia Society","funders":"","keywords":"Medicine; Haemophilia; Genetic enhancement; Haemophilia A; Virology; Pediatrics; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02535437,0.0009902819,0.002507547,0.001303012,0.001124804,0.005976306,0.002043827,0.006681183,0.007225652],"category_scores_gemma":[0.02654887,0.0003192986,0.0009526119,0.001185299,0.007713222,0.01044034,0.003202897,0.01162058,0.003263507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002898514,"about_ca_system_score_gemma":0.005954136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000730667,"about_ca_topic_score_gemma":0.0009113655,"domain_scores_codex":[0.9915262,0.003543601,0.0005139347,0.0005941507,0.003256524,0.0005656739],"domain_scores_gemma":[0.9811949,0.0103781,0.001190881,0.001592335,0.003829312,0.001814555],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001050533,0.0006125409,0.000850735,0.006435412,0.0002666769,0.0004565262,0.000933719,0.0008852485,0.005170905,0.1699553,0.2346629,0.5787195],"study_design_scores_gemma":[0.000202984,0.0006313926,0.0004620381,0.004499608,0.0001191664,0.0004595017,0.0005578204,0.0003042007,0.001532691,0.1013026,0.8898704,0.00005757973],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.002006362,0.5944734,0.008541863,0.3717096,0.01424203,0.00008196021,0.0001578365,0.0002451453,0.008541737],"genre_scores_gemma":[0.03867337,0.7396829,0.009232782,0.1733313,0.0311252,0.0002259303,0.0003584215,0.0002764044,0.007093735],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9746456,"threshold_uncertainty_score":0.1340883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2012430275590101,"score_gpt":0.3568000679925717,"score_spread":0.1555570404335617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}