{"id":"W3085896652","doi":"10.1007/s11136-020-02623-1","title":"Changes in patient functioning and disability: results from a phase 3, double-blind, randomized, placebo-controlled clinical trial evaluating galcanezumab for chronic migraine prevention (REGAIN)","year":2020,"lang":"en","type":"article","venue":"Quality of Life Research","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eli Lilly and Company","keywords":"Placebo; Migraine; Medicine; Chronic Migraine; Internal medicine; Quality of life (healthcare); Repeated measures design; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002573272,0.001539854,0.003050119,0.0004041671,0.0005300725,0.0009043278,0.0007664958,0.001831895,0.004769859],"category_scores_gemma":[0.002443039,0.0004828433,0.001903854,0.0003713308,0.001140361,0.0007761199,0.0003061946,0.00209241,0.0006790073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006015672,"about_ca_system_score_gemma":0.0008642549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006588425,"about_ca_topic_score_gemma":0.001594948,"domain_scores_codex":[0.9989144,0.0006045956,0.00008136495,0.0001769531,0.0001088559,0.0001139474],"domain_scores_gemma":[0.9982809,0.0004967962,0.0005407208,0.0001215387,0.0001397251,0.0004203291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9751409,0.006850133,0.0008016808,0.0005809489,0.001018534,0.0000307445,0.00003546766,0.0001495071,0.003323225,0.00002410967,0.0003634733,0.01168128],"study_design_scores_gemma":[0.932911,0.06096484,0.004798849,0.00002024164,0.0005058876,0.00003116307,0.00001200003,0.0001662673,0.0003363524,0.00003735451,0.000204531,0.00001147595],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903958,0.004366752,0.000406333,0.0003525997,0.0002115711,0.002140876,0.0009311304,0.0001043041,0.001090718],"genre_scores_gemma":[0.9925463,0.001631748,0.0008674318,0.000625796,0.0002733343,0.002376939,0.0008198409,0.0000189309,0.0008397661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004769859,"threshold_uncertainty_score":0.01595676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6070549897591327,"score_gpt":0.5814425232642805,"score_spread":0.02561246649485227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}