{"id":"W3086123339","doi":"10.25251/skin.4.supp.45","title":"Durable Efficacy of Certolizumab Pegol Dosed at 400 mg Every Two Weeks Over 128 Weeks in Patients with Plaque Psoriasis Enrolled in Three Phase 3 Trials (CIMPASI-1, CIMPASI-2 and CIMPACT)","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre de Recherche Dermatologique du Québec Métropolitain","funders":"UCB Pharma; Dermira","keywords":"Certolizumab pegol; Plaque psoriasis; Medicine; Psoriasis; Internal medicine; Dermatology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001553262,0.0004867249,0.001506138,0.0001854146,0.000297771,0.0007313013,0.0003798525,0.001174065,0.004597345],"category_scores_gemma":[0.001289546,0.0002721406,0.001254967,0.0002675392,0.0003820136,0.0008039786,0.0001878814,0.002771123,0.0008333626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004558746,"about_ca_system_score_gemma":0.0006113123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008055381,"about_ca_topic_score_gemma":0.001635986,"domain_scores_codex":[0.9996533,0.00012721,0.00001832463,0.00006968648,0.00003503682,0.00009634506],"domain_scores_gemma":[0.9991817,0.0002310239,0.0001819552,0.00008644359,0.00005319625,0.0002656061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5316292,0.01327417,0.007876786,0.001437844,0.002515126,0.0003925211,0.0002706427,0.00253892,0.04926961,0.0003895078,0.01164044,0.3787653],"study_design_scores_gemma":[0.5750626,0.3347921,0.06859086,0.0002324503,0.001510766,0.0007174728,0.0001082686,0.001936378,0.007609591,0.0006627396,0.008713239,0.00006355596],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765396,0.01243765,0.0009642906,0.00206949,0.00035671,0.0008083387,0.001942574,0.0003198861,0.00456146],"genre_scores_gemma":[0.9918494,0.00229704,0.0006444261,0.0011736,0.0001982069,0.0002539795,0.001403914,0.00002781258,0.002151638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004597345,"threshold_uncertainty_score":0.01537961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02122709589756228,"score_gpt":0.2733800801366297,"score_spread":0.2521529842390675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}