{"id":"W3086134091","doi":"","title":"Collaborative efforts to develop adverse outcome pathways: Oxidative DNA damage leading to chromosomal aberrations and mutations","year":2019,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Health Canada","funders":"","keywords":"Adverse Outcome Pathway; DNA damage; Oxidative damage; DNA repair; Oxidative phosphorylation; Outcome (game theory); DNA; Genetics; Oxidative stress; Bioinformatics; Computational biology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03264127,0.001261276,0.001161159,0.0024147,0.002103332,0.005206488,0.003313287,0.004828629,0.0162327],"category_scores_gemma":[0.02312215,0.0003213584,0.001778575,0.001400837,0.001957835,0.002892613,0.017621,0.004378822,0.003209758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002584582,"about_ca_system_score_gemma":0.01663902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001372226,"about_ca_topic_score_gemma":0.001309054,"domain_scores_codex":[0.989272,0.004328636,0.0006899732,0.00179017,0.002637116,0.001282063],"domain_scores_gemma":[0.9594684,0.007804506,0.004065783,0.006779299,0.01050924,0.01137278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001366158,0.002529887,0.03130035,0.003451614,0.0007101819,0.001531111,0.00517445,0.005764786,0.03542978,0.05894517,0.06324117,0.7905554],"study_design_scores_gemma":[0.0006081171,0.003484427,0.03083328,0.002528656,0.00078216,0.00384262,0.01005996,0.005531919,0.07535817,0.1133728,0.7533623,0.0002355718],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1899633,0.05796459,0.4050515,0.1985641,0.01215592,0.004814426,0.001822696,0.002076456,0.127587],"genre_scores_gemma":[0.6049344,0.04035456,0.2587189,0.02319537,0.005445148,0.002849213,0.004423323,0.000587036,0.05949208],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03264127,"threshold_uncertainty_score":0.1726255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362211522373682,"score_gpt":0.250814210233626,"score_spread":0.2371920950098892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}