{"id":"W3086258129","doi":"10.1016/s1470-2045(20)30446-0","title":"Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial","year":2020,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":482,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Institut Claudius Regaud; Radboud Universitair Medisch Centrum; Universitair Medisch Centrum Groningen; European Organisation for Research and Treatment of Cancer; Leids Universitair Medisch Centrum; Royal Marsden NHS Foundation Trust; European Commission; Herlev Hospital; Radboud Universiteit; Universiteit Leiden","keywords":"Medicine; Radiation therapy; Clinical endpoint; Surgery; Randomized controlled trial; Sarcoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001553376,0.002247357,0.002801564,0.0004123519,0.000382998,0.001119257,0.0008699475,0.00199481,0.01063345],"category_scores_gemma":[0.001753022,0.0007041741,0.003246841,0.0004622809,0.001310012,0.00129571,0.0005833366,0.004028045,0.001600298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008522581,"about_ca_system_score_gemma":0.0009355445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001550935,"about_ca_topic_score_gemma":0.004133102,"domain_scores_codex":[0.9993864,0.0003635553,0.00002839317,0.0001012043,0.00003256799,0.00008796452],"domain_scores_gemma":[0.9992214,0.0002834878,0.0001793911,0.00005555985,0.00003064382,0.0002294483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9829259,0.002183113,0.0002750297,0.0007318426,0.001053214,0.00001972909,0.00004592536,0.0003882937,0.0009159158,0.0001158936,0.000846809,0.01049839],"study_design_scores_gemma":[0.9488545,0.04839016,0.001002819,0.0000554966,0.0005161388,0.00002468798,0.00003185012,0.000292193,0.0001189603,0.0002384805,0.0004583779,0.00001634357],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792768,0.008657536,0.001045603,0.001767349,0.001457237,0.00285152,0.001725868,0.0001991069,0.00301904],"genre_scores_gemma":[0.9819643,0.003964754,0.001693348,0.001869627,0.0005348039,0.003013326,0.001346832,0.00004431423,0.005568606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01063345,"threshold_uncertainty_score":0.03557241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1237764134445484,"score_gpt":0.3730701604643574,"score_spread":0.2492937470198091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}