{"id":"W3086258129","doi":"10.1016/s1470-2045(20)30446-0","title":"Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial","year":2020,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":482,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Institut Claudius Regaud; Radboud Universitair Medisch Centrum; Universitair Medisch Centrum Groningen; European Organisation for Research and Treatment of Cancer; Leids Universitair Medisch Centrum; Royal Marsden NHS Foundation Trust; European Commission; Herlev Hospital; Radboud Universiteit; Universiteit Leiden","keywords":"Medicine; Radiation therapy; Clinical endpoint; Surgery; Randomized controlled trial; Sarcoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007480198,0.0003752502,0.00233413,0.00006258104,0.0002166746,0.00006833408,0.0002872162,0.0001591008,0.0002119997],"category_scores_gemma":[0.0005726084,0.0002206047,0.0002010359,0.0002380128,0.0002076751,0.0001532983,0.00008583657,0.000281512,0.00001357832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005882003,"about_ca_system_score_gemma":0.001018179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007609831,"about_ca_topic_score_gemma":0.00004911912,"domain_scores_codex":[0.9971946,0.0006184781,0.0006416352,0.0005701069,0.0003397461,0.000635442],"domain_scores_gemma":[0.9929155,0.005783234,0.0003578195,0.0004666757,0.0001937653,0.0002830227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9118149,0.007220708,0.01382437,0.00008760061,0.001454199,0.000236251,0.0007722282,0.000003913039,0.00009518724,0.00002260374,0.03273126,0.03173676],"study_design_scores_gemma":[0.9435398,0.01367347,0.007846797,0.00007955584,0.0007497202,0.00001622105,0.0001046476,0.0003613924,0.0002627242,0.000003588143,0.03306217,0.0002998876],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97689,0.001367931,0.00006434718,0.01162563,0.0008070208,0.00855565,0.0002099671,0.00008061449,0.000398812],"genre_scores_gemma":[0.9835746,0.00113865,0.003019503,0.006916439,0.002047545,0.002341371,0.000819483,0.00008953475,0.00005289282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03172491,"threshold_uncertainty_score":0.8995999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1237764134445484,"score_gpt":0.3730701604643574,"score_spread":0.2492937470198091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}