{"id":"W3086870866","doi":"10.1124/molpharm.120.000098","title":"Heparin-binding Peptides as Novel Therapies to Stop SARS-CoV-2 Cellular Entry and Infection","year":2020,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Institutes of Health; W. Garfield Weston Foundation; Weston Brain Institute","keywords":"Heparin; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); Virology; Computational biology; Chemistry; Medicine; Biology; Biochemistry; Infectious disease (medical specialty); Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005226085,0.0009468069,0.001460721,0.001182599,0.0001493508,0.0008308637,0.0006850643,0.0009597141,0.003941694],"category_scores_gemma":[0.0005022998,0.0002365588,0.0004214855,0.001053727,0.0003480595,0.0008808539,0.0004353987,0.002422051,0.001865573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004445295,"about_ca_system_score_gemma":0.0007126161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007411096,"about_ca_topic_score_gemma":0.001672687,"domain_scores_codex":[0.9998931,0.00001841056,0.00001298585,0.00001591618,0.00004095201,0.00001864161],"domain_scores_gemma":[0.9998714,0.00005893162,0.00002307505,0.000003893298,0.00002844992,0.00001420723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002906167,0.000190998,0.0000775549,0.01008106,0.0001340343,0.0001253499,0.00003094243,0.0004589948,0.003432451,0.003292865,0.03359787,0.9482872],"study_design_scores_gemma":[0.0003013135,0.0005415889,0.0007213721,0.003481306,0.0003552024,0.0006808282,0.00004335541,0.0002699167,0.00145546,0.002327367,0.9897934,0.00002893894],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000277548,0.9975637,0.0002194591,0.0002829616,0.0003414129,0.00001399334,0.00003654851,0.0000144739,0.001249824],"genre_scores_gemma":[0.00129549,0.9965826,0.0003211061,0.0004190462,0.0002346369,0.00001773072,0.00006700788,0.000002110274,0.001060303],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003941694,"threshold_uncertainty_score":0.01318628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07141011932785672,"score_gpt":0.4194782174717072,"score_spread":0.3480680981438504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}