{"id":"W3086925430","doi":"10.7554/elife.58828.sa1","title":"Decision letter: EDF1 coordinates cellular responses to ribosome collisions","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Ribosome; Translation (biology); Computational biology; Cell biology; Biology; Computer science; Genetics; RNA; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008509553,0.0008386888,0.002214385,0.001570172,0.004956346,0.007679842,0.003369262,0.04133317,0.06446406],"category_scores_gemma":[0.06163972,0.001069524,0.001770967,0.0008725688,0.002681007,0.002501301,0.002456912,0.0164692,0.04313823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005229152,"about_ca_system_score_gemma":0.01056747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005466425,"about_ca_topic_score_gemma":0.01127658,"domain_scores_codex":[0.9923826,0.001063868,0.0006190961,0.0005881553,0.003962602,0.001383674],"domain_scores_gemma":[0.9702966,0.01110089,0.001093925,0.00150613,0.009636416,0.00636603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009610299,0.00002042367,0.00007428771,0.00004581178,0.000008595,0.0002606472,0.00001536682,0.00003460325,0.0001324677,0.001273876,0.992651,0.005386786],"study_design_scores_gemma":[0.0001482804,0.00004380368,0.0006331498,0.0001282803,0.00002113668,0.0002336659,0.00004932511,0.0004736527,0.0005985642,0.003873955,0.9937604,0.00003568626],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.0009357853,0.001355476,0.0007500143,0.5728329,0.3964668,0.0002053157,0.001230097,0.0004512903,0.02577231],"genre_scores_gemma":[0.01594578,0.00322948,0.002300755,0.4618951,0.2366802,0.0004493481,0.001339768,0.0003554338,0.2778041],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.06446406,"threshold_uncertainty_score":0.2156538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02674453028011516,"score_gpt":0.315164272360565,"score_spread":0.2884197420804499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}