{"id":"W3087210493","doi":"10.1056/nejmoa2027071","title":"Osimertinib in Resected <i>EGFR</i> -Mutated Non–Small-Cell Lung Cancer","year":2020,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1756,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Chugai Pharmaceutical; EMD Serono; Genentech; Ono Pharmaceutical; Shionogi; Loxo Oncology; Astellas Pharma; Mirati Therapeutics; Daiichi Sankyo Europe; Sanofi; Halozyme; F. Hoffmann-La Roche; Taiho Pharmaceutical; Regeneron Pharmaceuticals; Spectrum Pharmaceuticals; Amgen; Kyorin Pharmaceutical; Pfizer; Symphogen; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Osimertinib; Lung cancer; Medicine; Cancer research; Oncology; Internal medicine; Cancer; Epidermal growth factor receptor; Erlotinib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006185542,0.0003364139,0.000565009,0.0001205948,0.000146888,0.0002723875,0.0001598125,0.000276637,0.001125999],"category_scores_gemma":[0.0005036528,0.0001095081,0.0003889674,0.0001063703,0.0001632834,0.000191208,0.0001405044,0.0004731425,0.0001555792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004579404,"about_ca_system_score_gemma":0.0004608609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000363491,"about_ca_topic_score_gemma":0.0009895378,"domain_scores_codex":[0.999849,0.00006767819,0.00001521618,0.00001928563,0.00002065322,0.00002811996],"domain_scores_gemma":[0.9998372,0.00003561549,0.00005246303,0.000007837156,0.00001219483,0.00005476105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4434836,0.007460885,0.0679066,0.001588857,0.001524862,0.001143961,0.0002791516,0.003441894,0.0489041,0.0005557709,0.007794605,0.4159157],"study_design_scores_gemma":[0.285185,0.4004923,0.2572469,0.0003892092,0.003067896,0.003666997,0.0002696904,0.006595837,0.02017008,0.001253721,0.02161057,0.00005205684],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951808,0.003345447,0.0001517756,0.0002800425,0.0001002753,0.0001257219,0.00007693754,0.00001401538,0.0007249884],"genre_scores_gemma":[0.9976676,0.001377307,0.0001621901,0.0001632702,0.00008016093,0.00009678314,0.0001041971,0.00000215177,0.0003463507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001125999,"threshold_uncertainty_score":0.003766835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02115782651282301,"score_gpt":0.3285523371855753,"score_spread":0.3073945106727523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}