{"id":"W3087230035","doi":"10.1128/jvi.01428-20","title":"An Early Microglial Response Is Needed To Efficiently Control Herpes Simplex Virus Encephalitis","year":2020,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Herpes simplex virus; Macrophage colony-stimulating factor; Chemokine; Microglia; Immunology; Cytokine; Encephalitis; Ratón; Interferon; Receptor; Virus; Internal medicine; Endocrinology; Macrophage; Inflammation; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000278644,0.0004480114,0.0006052179,0.0001849917,0.0002716429,0.0005525887,0.0001277945,0.0005340967,0.001399155],"category_scores_gemma":[0.0002998041,0.00009403787,0.0002169241,0.00008564685,0.0002471101,0.0003514935,0.0002581952,0.0008103349,0.0004099854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002748936,"about_ca_system_score_gemma":0.0004981908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004363953,"about_ca_topic_score_gemma":0.0005615261,"domain_scores_codex":[0.9997309,0.00006759899,0.0000213241,0.00002150746,0.00005284393,0.0001058473],"domain_scores_gemma":[0.9998956,0.00001892732,0.00002928156,0.00000853787,0.00001957311,0.00002806126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005303839,0.0002232253,0.0008400816,0.0004420943,0.00001943462,0.0002538863,0.00005732255,0.0002591707,0.9635917,0.0006050347,0.0005126919,0.03266506],"study_design_scores_gemma":[0.000318095,0.00670549,0.04823153,0.001009815,0.0002117856,0.002995423,0.0007635806,0.003335157,0.8561649,0.003998757,0.07621237,0.00005303722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9011234,0.07702231,0.008375081,0.002567436,0.0007755469,0.0003175124,0.0002836415,0.0004286356,0.009106444],"genre_scores_gemma":[0.9785905,0.01462044,0.003905686,0.0004487435,0.0002846466,0.0001300166,0.0001468388,0.00002455013,0.001848563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001399155,"threshold_uncertainty_score":0.004680634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01920565186185679,"score_gpt":0.3156688468566863,"score_spread":0.2964631949948295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}