{"id":"W3087357547","doi":"10.1007/s13238-020-00786-8","title":"Pioneer of prostate cancer: past, present and the future of FOXA1","year":2020,"lang":"en","type":"review","venue":"Protein & Cell","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"National Cancer Institute","keywords":"FOXA1; Prostate cancer; Androgen receptor; Transcription factor; Cancer research; Chromatin; Cancer; Prostate; Biology; Androgen deprivation therapy; Medicine; Breast cancer; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002221072,0.0002850762,0.001544935,0.00007664561,0.00003770153,0.0000102671,0.0001648219,0.000148539,0.00007679782],"category_scores_gemma":[0.000007545853,0.0001360383,0.0003077271,0.0002856705,0.0002915761,0.00002372403,0.000159204,0.0004335786,0.000006423242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006637659,"about_ca_system_score_gemma":0.0005773889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001088605,"about_ca_topic_score_gemma":0.00000182348,"domain_scores_codex":[0.9983979,0.0001598846,0.000475378,0.0003141523,0.0004157295,0.0002369978],"domain_scores_gemma":[0.9989554,0.00007125521,0.0003661494,0.0003457881,0.0001373263,0.0001240999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004905171,0.00009282567,0.00002529817,0.08283424,0.0003390662,0.00002757515,0.0004593787,1.076006e-7,0.00003447634,0.00003806807,0.002344892,0.9133136],"study_design_scores_gemma":[0.002083912,0.0002651241,0.000003710549,0.008020411,0.000849489,0.000006797625,0.00006062209,0.000003992537,0.001123634,0.00004532675,0.9874256,0.000111346],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005832766,0.9878104,0.000001127921,0.004026875,0.00006968119,0.007137603,0.0001364649,0.00001301821,0.0007464743],"genre_scores_gemma":[0.0001109831,0.9914541,0.0000929294,0.00001416174,0.0008706799,0.001444032,0.00005672915,0.0000447862,0.0059116],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9850807,"threshold_uncertainty_score":0.5547481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02626100797590298,"score_gpt":0.3287618782701934,"score_spread":0.3025008702942904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}