{"id":"W3087357547","doi":"10.1007/s13238-020-00786-8","title":"Pioneer of prostate cancer: past, present and the future of FOXA1","year":2020,"lang":"en","type":"review","venue":"Protein & Cell","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"National Cancer Institute","keywords":"FOXA1; Prostate cancer; Androgen receptor; Transcription factor; Cancer research; Chromatin; Cancer; Prostate; Biology; Androgen deprivation therapy; Medicine; Breast cancer; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004227434,0.000458463,0.0007048401,0.001227062,0.0002317967,0.0007701211,0.0004755874,0.0005968824,0.003320083],"category_scores_gemma":[0.0004847932,0.0001778803,0.0003584324,0.001183441,0.0003821012,0.001149824,0.0004722639,0.001473456,0.001452182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000590155,"about_ca_system_score_gemma":0.001090827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001451306,"about_ca_topic_score_gemma":0.00283175,"domain_scores_codex":[0.9998854,0.00002281896,0.00001233212,0.00002245535,0.00004187888,0.00001513955],"domain_scores_gemma":[0.9998364,0.00006715707,0.0000183959,0.000005055722,0.00004773699,0.0000251259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001014694,0.00003345655,0.0002537246,0.01214272,0.00007326039,0.0001517454,0.0000992935,0.0002033438,0.001744775,0.006281737,0.0458552,0.9330593],"study_design_scores_gemma":[0.00000812901,0.00004488275,0.0005504877,0.001731685,0.00004055259,0.0004998664,0.00003874548,0.0000403166,0.000196582,0.001331109,0.9955093,0.000008376453],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001089424,0.9982435,0.00005869153,0.0004884335,0.00024951,0.000001516138,0.00001289958,0.000004717861,0.000831773],"genre_scores_gemma":[0.0005989011,0.9982572,0.00008097017,0.0002515935,0.0001499496,0.00000213489,0.00001888627,0.00000151406,0.0006388064],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003320083,"threshold_uncertainty_score":0.01110673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02626100797590298,"score_gpt":0.3287618782701934,"score_spread":0.3025008702942904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}