{"id":"W3087404059","doi":"10.1186/s12985-020-01408-9","title":"Role of HVR1 sequence similarity in the cross-genotypic neutralization of HCV","year":2020,"lang":"en","type":"article","venue":"Virology Journal","topic":"Hepatitis C virus research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Neutralization; Immunogen; Virology; Epitope; Biology; Antibody; Neutralizing antibody; Immunology; Virus; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003166983,0.0001712538,0.0001512434,0.0001876426,0.00009216555,0.0003172111,0.0001527809,0.000282674,0.0008613035],"category_scores_gemma":[0.0003312865,0.00008418135,0.0001934984,0.0000693389,0.0001880338,0.0001728133,0.0001910402,0.0002748121,0.0002218661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001718582,"about_ca_system_score_gemma":0.0001188221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003461539,"about_ca_topic_score_gemma":0.0002866551,"domain_scores_codex":[0.9998117,0.00005975433,0.00001368726,0.0000306228,0.00003783055,0.00004645247],"domain_scores_gemma":[0.9998098,0.00005207136,0.00005901071,0.00002417699,0.0000163756,0.00003867755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003118031,0.00005546014,0.007773136,0.00004397576,0.00001900635,0.0002371919,0.00004427289,0.0002684253,0.9870025,0.0003012175,0.00003462828,0.003908399],"study_design_scores_gemma":[0.00004150069,0.001791463,0.2779526,0.00004257656,0.00008581423,0.007097641,0.000163135,0.005941295,0.7035353,0.0005423322,0.002781197,0.00002528935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997267,0.0009275443,0.0003664818,0.00002713696,0.000007531912,0.000007259468,0.00003224143,0.000009538659,0.001355259],"genre_scores_gemma":[0.9995906,0.00008321051,0.0001169078,0.00003130048,0.000003812586,0.000001035574,0.00002576888,0.00000177243,0.0001455883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008613035,"threshold_uncertainty_score":0.002881408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08474914489083574,"score_gpt":0.3864984458268955,"score_spread":0.3017493009360597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}