{"id":"W3087533766","doi":"10.1016/j.humpath.2020.09.002","title":"Lack of distinct molecular profile of Primary Dermal Melanoma","year":2020,"lang":"en","type":"article","venue":"Human Pathology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"National Cancer Institute; American Skin Association","keywords":"GNAQ; Neuroblastoma RAS viral oncogene homolog; Melanoma; Cancer research; Biology; Mutation testing; Mutation; Pathology; Medicine; Genetics; Gene; KRAS","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005839698,0.00008268443,0.0003179452,0.00005539613,0.00001859157,0.000001380419,0.00006287028,0.00005631871,0.00059053],"category_scores_gemma":[0.00003628628,0.00007720559,0.00008030375,0.00007965228,0.0001045926,0.000009916092,0.00007459404,0.00008840035,0.00003461719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001475062,"about_ca_system_score_gemma":0.00002200776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004516826,"about_ca_topic_score_gemma":0.000001661878,"domain_scores_codex":[0.9992893,0.00004536255,0.0002598377,0.000173673,0.0001148414,0.0001169713],"domain_scores_gemma":[0.9995798,0.00001162162,0.0001129912,0.0001825204,0.00004640241,0.00006669927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002419525,0.0001868816,0.006781177,0.000659625,0.00006379008,0.002107844,0.0004997653,0.000002779382,0.9814692,0.002866541,0.001563818,0.003556618],"study_design_scores_gemma":[0.006317465,0.007806875,0.3584889,0.0001184449,0.0006087783,0.0022745,0.0004330694,0.0002274117,0.5969058,0.0005347407,0.02580629,0.0004777209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9586855,0.00008931697,0.0006714292,0.0004995099,0.00004871682,0.0002767511,0.000009173805,0.0000410074,0.03967861],"genre_scores_gemma":[0.9977648,0.000002526124,0.000634816,0.0009646929,0.00004728175,0.000009707351,0.00003507036,0.00001387948,0.0005271981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3845634,"threshold_uncertainty_score":0.6465889,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04099182890310057,"score_gpt":0.2825773268273177,"score_spread":0.2415854979242171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}