{"id":"W3087545504","doi":"10.1002/2211-5463.12976","title":"Adipose‐derived mesenchymal stem cells differentiate into pancreatic cancer‐associated fibroblasts <i>in vitro</i>","year":2020,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Astellas Pharma; Institute of Genetics; Astellas Foundation for Research on Metabolic Disorders; Japan Agency for Medical Research and Development","keywords":"Mesenchymal stem cell; Tumor microenvironment; Cancer research; Cancer-Associated Fibroblasts; Adipose tissue; In vitro; Biology; Cell culture; Pancreatic cancer; Cell biology; Stroma; Cancer; Immunology; Tumor cells; Genetics; Endocrinology; Immunohistochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001797385,0.0002397934,0.0001915659,0.0001911962,0.0001343357,0.0003881567,0.00009998312,0.0001889972,0.0008846611],"category_scores_gemma":[0.000142828,0.00009653345,0.0002745746,0.0002291418,0.0001296938,0.0001689771,0.0001739621,0.0003818557,0.0005387315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000125097,"about_ca_system_score_gemma":0.0001835534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008579142,"about_ca_topic_score_gemma":0.001123828,"domain_scores_codex":[0.9998689,0.00001417172,0.00002240984,0.00002876657,0.00004375483,0.00002198021],"domain_scores_gemma":[0.9998958,0.00002560564,0.00001899787,0.00001978392,0.00002015751,0.00001972277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008191525,0.00003470383,0.001594168,0.00007455162,0.00000768612,0.0001362005,0.00007647875,0.0002162355,0.9919332,0.0001852948,0.000118782,0.005540806],"study_design_scores_gemma":[0.000008718984,0.0001668829,0.00663698,0.00001415617,0.00001815936,0.0002974011,0.00009855995,0.002377714,0.9842406,0.0001015741,0.00603203,0.000007221759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676782,0.001506259,0.02388204,0.00007882359,0.00007842686,0.0001056507,0.001485177,0.000222652,0.004962716],"genre_scores_gemma":[0.9726281,0.00111413,0.02043499,0.0001326886,0.00002513213,0.0001228099,0.001934389,0.00005644319,0.003551274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008846611,"threshold_uncertainty_score":0.00295943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04621433643440682,"score_gpt":0.328086882847005,"score_spread":0.2818725464125982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}