{"id":"W3087591417","doi":"10.1210/clinem/dgaa658","title":"Genome-Wide Association for HbA1c in Malay Identified Deletion on <i>SLC4A1</i> that Influences HbA1c Independent of Glycemia","year":2020,"lang":"en","type":"review","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Public Health Ontario; University of Toronto","funders":"Biomedical Research Council; National University Health System; National Medical Research Council; National Research Foundation Singapore; National University of Singapore; Ministry of Health -Singapore","keywords":"Malay; Genetics; Genome-wide association study; Biology; Genetic association; Association (psychology); Gene; Psychology; Genotype; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003204886,0.0002842007,0.0002839616,0.0004650426,0.0003140123,0.0002915554,0.0002471429,0.0002430052,0.003151009],"category_scores_gemma":[0.0006979589,0.0001395021,0.0009015507,0.0006123287,0.0002202463,0.00009986811,0.0003748262,0.0003811015,0.0002467807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002808141,"about_ca_system_score_gemma":0.0003777141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01395877,"about_ca_topic_score_gemma":0.01976973,"domain_scores_codex":[0.9998336,0.00003071958,0.000020007,0.00005591862,0.00003045489,0.00002923017],"domain_scores_gemma":[0.9996512,0.00009073118,0.0001242556,0.00003941985,0.0000324274,0.00006192405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003012726,0.0001010436,0.8815365,0.0003203649,0.001986799,0.002750799,0.0003830196,0.0004851437,0.09233017,0.0003309204,0.001528947,0.01523356],"study_design_scores_gemma":[0.00005428668,0.0001166745,0.9910624,0.00003172432,0.0008765912,0.001955965,0.0000802994,0.001009278,0.004001917,0.00009407604,0.0007000392,0.00001677238],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9976739,0.0003180276,0.0003881115,0.00009395832,0.00001110483,0.000009906487,0.0009802551,0.00001750116,0.0005073413],"genre_scores_gemma":[0.9985427,0.0001441933,0.000490552,0.00006692156,0.000008000374,0.000008871549,0.000475193,0.000007044936,0.0002565845],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01395877,"threshold_uncertainty_score":0.02775508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08091107858289816,"score_gpt":0.4001653885995203,"score_spread":0.3192543100166222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}