{"id":"W3087752070","doi":"10.1371/journal.ppat.1008328","title":"Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans","year":2020,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stockholms Universitet; Hospital for Sick Children; Vetenskapsrådet","keywords":"Biochemistry; Biology; Candida albicans; Glutamate dehydrogenase; Cell biology; Virulence; Amino acid; Chemistry; Microbiology; Glutamate receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007879294,0.0003574605,0.0002974232,0.0001951513,0.0001725591,0.000532017,0.0003931574,0.0002755706,0.0009489512],"category_scores_gemma":[0.0001606146,0.0001790785,0.0002356379,0.0001989392,0.0002506571,0.0001608994,0.000530703,0.0005123043,0.0004238476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003590636,"about_ca_system_score_gemma":0.0004267152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00193893,"about_ca_topic_score_gemma":0.002403761,"domain_scores_codex":[0.9998337,0.00001733802,0.00002120906,0.00003617785,0.00005100546,0.00004050652],"domain_scores_gemma":[0.9997784,0.00002369365,0.00005918702,0.00003389812,0.00002238729,0.00008227324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008384736,0.00001209476,0.0003097255,0.00002039602,0.00000303927,0.00008158418,0.00000923788,0.00002578024,0.9988681,0.00005301195,0.00003599232,0.0004971874],"study_design_scores_gemma":[0.00002801167,0.0001170085,0.02204109,0.00001806566,0.00001766573,0.0008017323,0.0001243664,0.00152169,0.9723531,0.00009751397,0.002862849,0.00001686769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966799,0.0007532368,0.0009368138,0.00008939701,0.00002150041,0.00001122202,0.0007011772,0.00007827133,0.000728521],"genre_scores_gemma":[0.9964747,0.0003033243,0.0008158612,0.00005383251,0.00000577887,0.00002064035,0.0008004588,0.00003712667,0.001488164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00193893,"threshold_uncertainty_score":0.003855288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03244892627740665,"score_gpt":0.2601226228927473,"score_spread":0.2276736966153407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}