{"id":"W3087752070","doi":"10.1371/journal.ppat.1008328","title":"Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans","year":2020,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Stockholms Universitet; Hospital for Sick Children; Vetenskapsrådet","keywords":"Biochemistry; Biology; Candida albicans; Glutamate dehydrogenase; Cell biology; Virulence; Amino acid; Chemistry; Microbiology; Glutamate receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007351903,0.0001528593,0.0003635185,0.00002037406,0.00007210726,0.00001455094,0.00007424493,0.00007847685,0.0003779251],"category_scores_gemma":[0.0001868431,0.0001354096,0.00008298142,0.0001114853,0.0000843183,0.00006870588,0.00003851781,0.00007077509,0.00001360287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002812696,"about_ca_system_score_gemma":0.00005695674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001246486,"about_ca_topic_score_gemma":0.00007160896,"domain_scores_codex":[0.9988006,0.00002264015,0.0002902947,0.0004082278,0.000260435,0.0002178324],"domain_scores_gemma":[0.9992529,0.00007669697,0.0001064537,0.0002332505,0.0001098738,0.0002208725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003885233,0.0001245482,0.09370272,0.0003061876,0.00008584,0.00002031024,0.00104795,0.000002096138,0.9030639,0.00002077053,0.0006599023,0.0005772858],"study_design_scores_gemma":[0.001769752,0.000463036,0.01741284,0.000148745,0.0004827677,0.000002609664,0.000663488,0.006211101,0.9716127,0.0001923489,0.0007917811,0.0002488268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925609,0.001384077,0.001935476,0.0008755978,0.00002221428,0.000532027,0.00255171,0.00003476024,0.0001032461],"genre_scores_gemma":[0.9971213,0.0005243409,0.0009571134,0.0009663036,0.00005907577,0.0000226833,0.0001609606,0.00002618959,0.0001620405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07628988,"threshold_uncertainty_score":0.5521845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03244892627740665,"score_gpt":0.2601226228927473,"score_spread":0.2276736966153407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}