{"id":"W3087814557","doi":"10.1016/j.annonc.2020.08.1666","title":"1352P Circulating tumour (ct) DNA next generation sequencing (NGS) in advanced non-small cell lung cancer (mNSCLC): A UK single institution experience","year":2020,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Medicine; Lung cancer; T790M; Concordance; Oncology; Genotyping; Internal medicine; Cancer; ROS1; Genotype; Adenocarcinoma; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006525984,0.0003141494,0.0002990236,0.0003225035,0.0004424801,0.0008576702,0.0002299452,0.0003837014,0.002435589],"category_scores_gemma":[0.001965039,0.0001949861,0.0001974318,0.0004211108,0.0004444977,0.0004139306,0.0007537981,0.0005188,0.0005914684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009447248,"about_ca_system_score_gemma":0.0007824905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006995268,"about_ca_topic_score_gemma":0.01516096,"domain_scores_codex":[0.9995567,0.0001045129,0.0000424564,0.0001086294,0.0001115869,0.00007618953],"domain_scores_gemma":[0.9992212,0.0002236473,0.00007403052,0.00004900932,0.0001242648,0.0003079312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002600865,0.0006231942,0.3306811,0.000627792,0.0001366964,0.05481813,0.009334109,0.002424409,0.1055713,0.000708375,0.00784742,0.4846265],"study_design_scores_gemma":[0.000234398,0.005668951,0.6506478,0.0005546531,0.0003536034,0.2344453,0.005560778,0.005434278,0.03569477,0.00116993,0.06006948,0.0001660479],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868162,0.00310836,0.003169046,0.000840575,0.00005430033,0.00008840869,0.0003066388,0.0001081013,0.005508282],"genre_scores_gemma":[0.9908596,0.002038637,0.003614404,0.000419033,0.0000407603,0.00002175415,0.0003336994,0.0001026449,0.002569464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006995268,"threshold_uncertainty_score":0.0139091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0924449147374692,"score_gpt":0.3298265194009786,"score_spread":0.2373816046635094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}