{"id":"W3088069664","doi":"10.1002/hep4.1589","title":"Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease","year":2020,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Connecticut Children's Medical Center; University of Calgary; American Association for the Study of Liver Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Foundation for the National Institutes of Health","keywords":"Primary sclerosing cholangitis; Medicine; Autoimmune hepatitis; Gastroenterology; Internal medicine; Liver injury; Biomarker; Liver biopsy; Magnetic resonance cholangiopancreatography; Pathology; Transient elastography; Ulcerative colitis; Biopsy; Hepatitis; Endoscopic retrograde cholangiopancreatography; Disease; Pancreatitis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008274485,0.0004883896,0.0004870308,0.001031202,0.0001510378,0.0004470219,0.0002136827,0.0003918675,0.0004509212],"category_scores_gemma":[0.002390233,0.0002381842,0.0002671665,0.0006522307,0.0003042749,0.0004118281,0.0003313674,0.0003962934,0.000152877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002658457,"about_ca_system_score_gemma":0.000243209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009178179,"about_ca_topic_score_gemma":0.001176245,"domain_scores_codex":[0.9994412,0.0001888239,0.00007763223,0.00008699889,0.0001444759,0.00006072151],"domain_scores_gemma":[0.9986032,0.0004284142,0.0006189157,0.00003325695,0.0001631907,0.0001530653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001147672,0.00001263547,0.9930726,0.00002527877,0.00002600515,0.0002031939,0.00002915835,0.00007090335,0.002485654,0.00001280032,0.00006107544,0.003885921],"study_design_scores_gemma":[0.000008106199,0.000203565,0.9948443,0.00001360084,0.00004456837,0.001838212,0.0000686668,0.0007505976,0.001987489,0.00002380196,0.0002128388,0.000004183192],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978744,0.001571099,0.0002417539,0.00004374695,0.000006117671,0.000005084018,0.00007632405,0.0000105095,0.0001710722],"genre_scores_gemma":[0.9986608,0.0005079342,0.0006126181,0.00001717548,0.00001724242,0.000008578173,0.0001214895,0.00000243366,0.00005183909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001031202,"threshold_uncertainty_score":0.004375994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03793551341557068,"score_gpt":0.3022893854114589,"score_spread":0.2643538719958883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}