{"id":"W3088069664","doi":"10.1002/hep4.1589","title":"Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease","year":2020,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Connecticut Children's Medical Center; University of Calgary; American Association for the Study of Liver Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; Foundation for the National Institutes of Health","keywords":"Primary sclerosing cholangitis; Medicine; Autoimmune hepatitis; Gastroenterology; Internal medicine; Liver injury; Biomarker; Liver biopsy; Magnetic resonance cholangiopancreatography; Pathology; Transient elastography; Ulcerative colitis; Biopsy; Hepatitis; Endoscopic retrograde cholangiopancreatography; Disease; Pancreatitis; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001225373,0.0001518651,0.0003850586,0.0001743748,0.0001117562,0.000007671576,0.000359665,0.00009287243,0.0002161916],"category_scores_gemma":[0.0007018462,0.0001460877,0.0001183665,0.0005694184,0.0003269002,0.0001157086,0.0007008998,0.0002704499,0.00003305784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002712353,"about_ca_system_score_gemma":0.0002284629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005319922,"about_ca_topic_score_gemma":0.00002082393,"domain_scores_codex":[0.9987692,0.0003095056,0.0004115781,0.0002157035,0.0001069326,0.0001871154],"domain_scores_gemma":[0.997709,0.0005449506,0.0001294534,0.001275831,0.00009230825,0.0002484254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002594388,0.0005567403,0.9954194,0.0004352086,0.00007378127,0.00002797775,0.0005403922,1.913288e-7,0.000464781,0.0003097825,0.0005647917,0.001347527],"study_design_scores_gemma":[0.0008623628,0.0001469503,0.9923869,0.00005803068,0.0005914066,0.000007922314,0.00007964305,0.003894609,0.00009621927,0.000153875,0.001590456,0.0001316425],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9528401,0.02961862,0.00001896104,0.01652758,0.00001956847,0.0006060546,0.0002146233,0.00004763207,0.0001068758],"genre_scores_gemma":[0.9781544,0.01959415,0.0009862295,0.001021351,0.00001015875,0.00009506597,0.0000890543,0.00001823221,0.00003134572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02531434,"threshold_uncertainty_score":0.5957284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03793551341557068,"score_gpt":0.3022893854114589,"score_spread":0.2643538719958883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}