{"id":"W3088104678","doi":"10.2174/1573406416666200925141703","title":"Identification and Expression Analysis of CD73 Inhibitors in Cervical Cancer","year":2020,"lang":"en","type":"article","venue":"Medicinal Chemistry","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Higher Education Commision, Pakistan; Crohn's and Colitis Canada","keywords":"HeLa; Cytotoxicity; Cytotoxic T cell; MTT assay; Cell culture; Molecular biology; Western blot; Nucleotidase; Adenosine; Enzyme; Chemistry; Adenosine monophosphate; Dephosphorylation; Apoptosis; Cell; Biochemistry; Biology; Phosphatase; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000677137,0.00006644683,0.0001370369,0.00002066329,0.00001243074,0.00000319268,0.00006698094,0.00008154253,0.0000805166],"category_scores_gemma":[0.00005635332,0.00006009986,0.00003777153,0.0002153231,0.00004376577,0.000001816831,0.00004478155,0.00006515205,2.146917e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000506951,"about_ca_system_score_gemma":0.00002287052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003693498,"about_ca_topic_score_gemma":0.000002877485,"domain_scores_codex":[0.9994174,0.00001154285,0.0001913035,0.0001971173,0.0001068267,0.00007587176],"domain_scores_gemma":[0.9997383,0.000007436375,0.00006930944,0.00008883214,0.00002871672,0.00006743406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004278375,0.00001259217,0.04343621,0.00006814157,0.00004393507,0.000002430945,0.0001214483,0.0001566346,0.9547532,5.264703e-7,0.001114735,0.0002473816],"study_design_scores_gemma":[0.0002406589,0.0000190788,0.007783388,0.00002856789,0.0001109894,8.959383e-7,0.0001875915,0.0006593956,0.990147,0.000002911799,0.0007534994,0.00006602904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995444,0.003571132,0.0002911313,0.0004908597,0.00001405198,0.00002739556,0.000007404569,0.000003069461,0.0001509367],"genre_scores_gemma":[0.9993196,0.0001478937,0.00002273371,0.0001288363,0.0002505734,0.000006463232,0.00006113751,0.000004794039,0.0000580115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03565283,"threshold_uncertainty_score":0.2450801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01006253617763177,"score_gpt":0.2641232889082271,"score_spread":0.2540607527305953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}