{"id":"W3088110133","doi":"10.1016/j.annonc.2020.08.1601","title":"1287P Efficacy and safety of entrectinib in locally advanced/metastatic ROS1 fusion-positive NSCLC: An updated integrated analysis","year":2020,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Roche (Canada)","funders":"F. Hoffmann-La Roche","keywords":"Medicine; ROS1; Oncology; Internal medicine; Cancer research; Cancer; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003987234,0.0006823266,0.003091139,0.001388564,0.0002046056,0.002105579,0.001086522,0.0006798021,0.002782232],"category_scores_gemma":[0.003580299,0.0004068435,0.004156727,0.002232559,0.0004209258,0.001686453,0.0007839925,0.001836804,0.0007542332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002316071,"about_ca_system_score_gemma":0.001570485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00220022,"about_ca_topic_score_gemma":0.009683019,"domain_scores_codex":[0.9984622,0.0002933093,0.0002308591,0.000278224,0.0005554605,0.0001798986],"domain_scores_gemma":[0.9970368,0.001003094,0.001025094,0.0001847139,0.0005792275,0.0001711028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.04492571,0.000551359,0.09365573,0.01117349,0.04648109,0.000256117,0.0001855257,0.006199823,0.007134339,0.001229017,0.02248196,0.7657258],"study_design_scores_gemma":[0.02599652,0.01465329,0.5729713,0.006939424,0.2045303,0.00210881,0.0002997782,0.006746301,0.006807687,0.00421529,0.1543222,0.0004090962],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5740832,0.3517677,0.00319249,0.006628235,0.0007665355,0.000766915,0.03583192,0.0004462731,0.02651672],"genre_scores_gemma":[0.8565928,0.09237721,0.003235473,0.004971289,0.000968748,0.0004075086,0.03709771,0.0001933962,0.004155843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003987234,"threshold_uncertainty_score":0.02108675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03654913715870304,"score_gpt":0.4069250868697754,"score_spread":0.3703759497110723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}