{"id":"W3088130337","doi":"10.3389/fvets.2020.577835","title":"Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses","year":2020,"lang":"en","type":"article","venue":"Frontiers in Veterinary Science","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"New Zealand Equine Research Foundation","keywords":"Myofibroblast; Transforming growth factor; Gene expression; Fibroblast; Biology; Extracellular matrix; Contractility; Wound healing; Granulation tissue; Fibrosis; Transforming growth factor beta; Growth factor; Pathology; Molecular biology; Cell biology; Cell culture; Immunology; Endocrinology; Medicine; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002258574,0.0002164945,0.0001710624,0.0001541517,0.0001064303,0.0001846718,0.00008673596,0.0001401421,0.001130806],"category_scores_gemma":[0.000186906,0.00007835969,0.0001922425,0.0001014772,0.0001395434,0.00007874351,0.000101634,0.0002815762,0.0002501581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008453474,"about_ca_system_score_gemma":0.00008995469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003971423,"about_ca_topic_score_gemma":0.0007846401,"domain_scores_codex":[0.999836,0.00005132567,0.00002349677,0.00002688205,0.0000310984,0.00003122938],"domain_scores_gemma":[0.9998204,0.00008445804,0.00002357566,0.00002308531,0.00002619369,0.00002227429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001295489,0.00003239062,0.0002511129,0.00003144365,0.000002431742,0.00006547041,0.00003340855,0.00002062098,0.9985706,0.000007917137,0.00001804275,0.0008371132],"study_design_scores_gemma":[0.00004476641,0.001563358,0.01851006,0.00001952325,0.0000294411,0.0005488909,0.0001343192,0.0004551496,0.9761692,0.00001921623,0.002500494,0.000005516704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968441,0.001142756,0.0005299914,0.00005287134,0.00002733267,0.00002972541,0.0002069742,0.000007190354,0.001159105],"genre_scores_gemma":[0.9933105,0.001217528,0.002330129,0.0001168223,0.00004126399,0.00006814887,0.0008907092,0.000007229481,0.00201782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001130806,"threshold_uncertainty_score":0.003782988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05832443781431429,"score_gpt":0.3132957658047538,"score_spread":0.2549713279904395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}