{"id":"W3088130337","doi":"10.3389/fvets.2020.577835","title":"Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses","year":2020,"lang":"en","type":"article","venue":"Frontiers in Veterinary Science","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"New Zealand Equine Research Foundation","keywords":"Myofibroblast; Transforming growth factor; Gene expression; Fibroblast; Biology; Extracellular matrix; Contractility; Wound healing; Granulation tissue; Fibrosis; Transforming growth factor beta; Growth factor; Pathology; Molecular biology; Cell biology; Cell culture; Immunology; Endocrinology; Medicine; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009570466,0.0001665014,0.0004315835,0.00035452,0.00007830031,0.00001222509,0.0002050665,0.0000783725,0.00005776353],"category_scores_gemma":[0.0001078137,0.0001487148,0.00008314732,0.0008884921,0.0003393708,0.0002355983,0.00004082029,0.0001825114,0.000005058909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339926,"about_ca_system_score_gemma":0.00025017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001265287,"about_ca_topic_score_gemma":8.751791e-7,"domain_scores_codex":[0.9986113,0.00004078165,0.0003713885,0.0003514608,0.0003026707,0.0003224071],"domain_scores_gemma":[0.9993694,0.00005519006,0.0001097323,0.000191356,0.00008070577,0.0001936589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002606007,0.0007130956,0.04234162,0.000322536,0.0001236692,0.0002242343,0.004618325,0.0009184776,0.9453822,0.00002042825,0.0001041181,0.00262528],"study_design_scores_gemma":[0.01004626,0.08292126,0.4058965,0.004332311,0.0003259912,0.0001901335,0.001822007,0.1406058,0.352378,0.0002323129,0.0004242336,0.0008251881],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954383,0.00009579267,0.003330705,0.0002890964,0.0002510625,0.0002535334,0.00005487611,0.00004224594,0.000244357],"genre_scores_gemma":[0.9933743,0.00002965489,0.006436517,0.00006558816,0.00002516679,0.000003168856,0.00001712649,0.00001378776,0.00003463294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5930042,"threshold_uncertainty_score":0.6064414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05832443781431429,"score_gpt":0.3132957658047538,"score_spread":0.2549713279904395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}