{"id":"W3088254913","doi":"10.1101/2020.09.25.313783","title":"Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Mechanotransduction; Cell biology; Extracellular matrix; Focal adhesion; Chemistry; Cell migration; Integrin; Biophysics; Biology; Cell; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000563569,0.00017147,0.00007733762,0.00007900367,0.00007382604,0.0001167982,0.00007841799,0.0001301562,0.0005170228],"category_scores_gemma":[0.00004846695,0.00006264654,0.0001101537,0.00005219221,0.0001085569,0.00008568966,0.00009928434,0.0001474741,0.00008402953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001622021,"about_ca_system_score_gemma":0.00008028268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005188626,"about_ca_topic_score_gemma":0.0009540556,"domain_scores_codex":[0.9999555,0.000004329228,0.000003919571,0.000007768607,0.0000174405,0.00001097089],"domain_scores_gemma":[0.9999427,0.00000836315,0.0000241225,0.000003945705,0.000007197457,0.00001384318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001286176,0.000003060316,0.0001167539,0.000008042307,7.903798e-7,0.00001074983,0.000004903138,0.00004964383,0.9996019,0.00001634858,0.000005113269,0.0001698087],"study_design_scores_gemma":[0.000002630491,0.00005706883,0.003852001,0.000002428421,0.000003249525,0.00005426127,0.0000212152,0.001189489,0.9944112,0.00001947112,0.0003841714,0.000002953023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987651,0.0001079389,0.000728983,0.00001858879,0.00000355229,0.000004289098,0.00006435659,0.00001347626,0.0002937129],"genre_scores_gemma":[0.9989554,0.00006208519,0.0005896621,0.000009441771,8.547898e-7,0.000007375164,0.00006629393,0.000002512626,0.0003063795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005188626,"threshold_uncertainty_score":0.001729548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649975959082503,"score_gpt":0.2323642660232589,"score_spread":0.2158645064324339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}