{"id":"W3088332612","doi":"10.1016/j.msard.2020.102492","title":"Shorter infusion time of ocrelizumab: Results from the randomized, double-blind ENSEMBLE PLUS substudy in patients with relapsing-remitting multiple sclerosis","year":2020,"lang":"en","type":"article","venue":"Multiple Sclerosis and Related Disorders","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Merck KGaA; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Novartis; Teva Pharmaceutical Industries; Bayer; Celgene; Biogen; Sanofi Genzyme; F. Hoffmann-La Roche; Agence Nationale de la Recherche; Roche; PTC Therapeutics; UCB","keywords":"Ocrelizumab; Medicine; Multiple sclerosis; Randomized controlled trial; Anesthesia; Clinical endpoint; Volunteer; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004300376,0.001022276,0.002507926,0.0003049698,0.0003136747,0.0006481752,0.0005393236,0.0009672895,0.001772479],"category_scores_gemma":[0.003367373,0.0004400679,0.002025688,0.0004296934,0.0007035167,0.001005571,0.0004379257,0.001500399,0.0002520529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004866681,"about_ca_system_score_gemma":0.0005416201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005983525,"about_ca_topic_score_gemma":0.001662814,"domain_scores_codex":[0.9981857,0.001071268,0.0002150042,0.0002722603,0.0001346244,0.0001211314],"domain_scores_gemma":[0.9973652,0.000748383,0.001010281,0.000352698,0.0001856459,0.0003378985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9533356,0.004139557,0.008562073,0.0006667759,0.004533207,0.00003453378,0.00009608987,0.0004378018,0.003507657,0.00004705394,0.000588031,0.0240515],"study_design_scores_gemma":[0.7410631,0.1929273,0.05042632,0.0001239994,0.01038172,0.0002158033,0.00007517667,0.0009393299,0.001913453,0.0001662554,0.001700437,0.00006705258],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948026,0.003465919,0.0002733484,0.0001092139,0.00009273038,0.0003475049,0.0005017639,0.00002602885,0.00038087],"genre_scores_gemma":[0.9950486,0.001630331,0.0008192151,0.0003365473,0.0002532193,0.0006565021,0.0009726342,0.00001002238,0.0002727815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004300376,"threshold_uncertainty_score":0.02274281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0457979791972268,"score_gpt":0.2463722815112125,"score_spread":0.2005743023139857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}