{"id":"W3088401235","doi":"10.1038/s41586-020-2797-4","title":"Cells of the adult human heart","year":2020,"lang":"en","type":"article","venue":"Nature","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1771,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institutes of Health; Alberta Innovates; China Scholarship Council; Bundesministerium für Bildung und Forschung; Deutsches Zentrum für Herz-Kreislaufforschung; European Commission; University of Alberta; Deutsche Forschungsgemeinschaft; Sarnoff Cardiovascular Research Foundation; British Heart Foundation; Howard Hughes Medical Institute; Chan Zuckerberg Initiative; Alexander von Humboldt-Stiftung; Wellcome Trust; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; Canadian Institutes of Health Research; National Science Foundation","keywords":"Transcriptome; Biology; Cell type; Myocyte; Immune system; Cell; Neuroscience; Human heart; Cardiac muscle; Cell biology; Cardiac Ventricle; Heart disease; Gene expression; Medicine; Pathology; Anatomy; Gene; Immunology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001562998,0.0002253328,0.0003296853,0.0004981962,0.000380681,0.001082727,0.0002837648,0.000447289,0.009423159],"category_scores_gemma":[0.0002501999,0.0001374736,0.000157209,0.0009521142,0.0003036084,0.0003836005,0.0007368374,0.000501684,0.01017299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000152316,"about_ca_system_score_gemma":0.000305967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007481806,"about_ca_topic_score_gemma":0.001270224,"domain_scores_codex":[0.9998289,0.00001482985,0.00001253372,0.0000607548,0.00006637955,0.00001651489],"domain_scores_gemma":[0.9999056,0.000008765978,0.00001408178,0.00002381625,0.00002513823,0.0000226289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003232043,0.00004760603,0.009721258,0.0009035282,0.00006600108,0.000771983,0.0008911591,0.0003875941,0.597068,0.0240552,0.0549987,0.3107658],"study_design_scores_gemma":[0.00002527291,0.00009445315,0.02742105,0.0001583465,0.00004003901,0.00226056,0.0004017677,0.0004118107,0.0448939,0.005863371,0.9184027,0.00002669005],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.2448628,0.1932458,0.1554632,0.00626337,0.004109619,0.0006044802,0.1184935,0.003394295,0.2735629],"genre_scores_gemma":[0.6496297,0.07515976,0.07359957,0.004552618,0.001121277,0.001110899,0.07772084,0.000516401,0.116589],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009423159,"threshold_uncertainty_score":0.03152364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007594184601800433,"score_gpt":0.2244998554222122,"score_spread":0.2169056708204117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}