{"id":"W3088632494","doi":"10.3389/fphys.2020.590180","title":"TFII-I/Gtf2i and Erythro-Megakaryopoiesis","year":2020,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Williams Syndrome Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; American Society of Hematology","keywords":"Macrocytosis; Gene; Biology; HES1; Transcription factor; Repressor; Transcription (linguistics); Erythropoiesis; Gene expression; Cancer research; Molecular biology; Genetics; Endocrinology; Internal medicine; Downregulation and upregulation; Medicine; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008189904,0.0001392186,0.000313577,0.000116185,0.00007438287,0.00001846466,0.0003359499,0.00009934332,0.00008848249],"category_scores_gemma":[0.0006097122,0.0001329514,0.00003884767,0.0004712789,0.0004573877,0.0001541988,0.0002499273,0.0002976851,0.0001012453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003668581,"about_ca_system_score_gemma":0.00003835414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001536899,"about_ca_topic_score_gemma":0.00000105664,"domain_scores_codex":[0.9983809,0.0002352711,0.000178641,0.000592369,0.0001623034,0.0004504981],"domain_scores_gemma":[0.9994494,0.000132597,0.00004000894,0.0002119015,0.00001239157,0.0001537159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001541089,0.00006006526,0.008463278,0.00007903728,0.000009939195,0.00008243087,0.0007338538,0.00004375524,0.9153704,0.0006231785,0.07050899,0.003870979],"study_design_scores_gemma":[0.006081965,0.002282733,0.3107873,0.00009767392,0.00003545862,0.0001660942,0.001781005,0.03246671,0.4655275,0.06304803,0.1156659,0.002059623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922626,0.0003491141,0.000398293,0.004419713,0.0005607636,0.0002555095,0.00002023945,0.0000814493,0.001652305],"genre_scores_gemma":[0.9961637,0.0003578079,0.001367151,0.001793748,0.0001035198,0.00002346607,0.000002545434,0.00002179379,0.0001662538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4498429,"threshold_uncertainty_score":0.54216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0342967456440876,"score_gpt":0.2683265326837015,"score_spread":0.2340297870396139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}