{"id":"W3088632494","doi":"10.3389/fphys.2020.590180","title":"TFII-I/Gtf2i and Erythro-Megakaryopoiesis","year":2020,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Williams Syndrome Research","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; American Society of Hematology","keywords":"Macrocytosis; Gene; Biology; HES1; Transcription factor; Repressor; Transcription (linguistics); Erythropoiesis; Gene expression; Cancer research; Molecular biology; Genetics; Endocrinology; Internal medicine; Downregulation and upregulation; Medicine; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009501967,0.0003224974,0.0002021464,0.0002110245,0.0001012441,0.0002897904,0.0002009396,0.0003727722,0.0005137238],"category_scores_gemma":[0.00009192312,0.00008246735,0.00009625851,0.0001430145,0.0003438883,0.0001875499,0.0001604635,0.0003553956,0.0002104883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003860248,"about_ca_system_score_gemma":0.0001822992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146067,"about_ca_topic_score_gemma":0.001306795,"domain_scores_codex":[0.9999552,0.000006334355,0.000002659058,0.0000135664,0.000007902495,0.00001443793],"domain_scores_gemma":[0.9999504,0.000005560158,0.00001498812,0.000001528502,0.000006873858,0.0000206194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006134482,0.00004814338,0.004317197,0.0004790721,0.00003945438,0.002138357,0.0002156748,0.0006005633,0.9418092,0.008626379,0.001827996,0.03928453],"study_design_scores_gemma":[0.0001566988,0.0008978263,0.1610988,0.0003978013,0.0001403728,0.008280098,0.0008145355,0.004201456,0.6951731,0.01742006,0.1113206,0.00009849372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7290697,0.2472456,0.007745739,0.001997593,0.0003450707,0.00001973257,0.0004149696,0.000161992,0.01299973],"genre_scores_gemma":[0.9400376,0.05040691,0.001520699,0.0001653063,0.0001108709,0.00001862131,0.0002709673,0.00001423316,0.007454852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00146067,"threshold_uncertainty_score":0.002904356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0342967456440876,"score_gpt":0.2683265326837015,"score_spread":0.2340297870396139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}