{"id":"W3088639284","doi":"10.1038/s42003-020-01253-0","title":"Highly efficient gene transfer in the mouse gut microbiota is enabled by the Incl2 conjugative plasmid TP114","year":2020,"lang":"en","type":"article","venue":"Communications Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Compute Canada","keywords":"Plasmid; Horizontal gene transfer; Biology; Microbiome; Genetics; Bacteria; Gene; Pilus; Bacterial conjugation; Gene transfer; Microbiology; Bacterial genetics; Genome; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003201481,0.0005011733,0.0002057448,0.0005320817,0.0001491301,0.0004421778,0.0001886943,0.0004338366,0.0007269432],"category_scores_gemma":[0.0002933829,0.0001715104,0.0002336613,0.0002070189,0.0002562951,0.0002209229,0.0004125277,0.0005302482,0.0002836091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001809372,"about_ca_system_score_gemma":0.0001522017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002559737,"about_ca_topic_score_gemma":0.000279671,"domain_scores_codex":[0.9996301,0.00008019951,0.00002557204,0.00008413474,0.0001059968,0.00007395953],"domain_scores_gemma":[0.999744,0.00004953803,0.0001037016,0.00003819761,0.00002327348,0.00004133637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002475232,0.00000895043,0.0001961551,0.000008022073,0.000001914515,0.00001453716,0.000006159859,0.00002809512,0.9990886,0.00003164741,0.000007577399,0.0005835718],"study_design_scores_gemma":[0.000003334082,0.0002335329,0.002040626,0.000003844619,0.00000748372,0.00008373393,0.00001766632,0.0004976234,0.9964185,0.00002945168,0.0006609017,0.000003373563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909242,0.0002742876,0.007708207,0.00004456998,0.00001158418,0.00003063118,0.000223315,0.0001875656,0.0005957619],"genre_scores_gemma":[0.9918332,0.0002315769,0.005655238,0.00002805026,0.000003889787,0.00003705516,0.0003347594,0.00005919643,0.001817002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007269432,"threshold_uncertainty_score":0.00243187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01699296501792371,"score_gpt":0.3042261348769247,"score_spread":0.287233169859001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}