{"id":"W3088761592","doi":"10.1016/j.trecan.2020.08.006","title":"Harnessing Real-World Evidence for the Development of Novel Cancer Therapies","year":2020,"lang":"en","type":"article","venue":"Trends in cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Real world evidence; Cancer; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2201585,0.001783122,0.004554871,0.01742856,0.002000176,0.02352135,0.005075128,0.00764806,0.01553179],"category_scores_gemma":[0.4907637,0.001770814,0.005113435,0.01008813,0.007412284,0.02364672,0.01833316,0.01375505,0.004052223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006151916,"about_ca_system_score_gemma":0.03133433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002729211,"about_ca_topic_score_gemma":0.004836848,"domain_scores_codex":[0.7947462,0.1528443,0.01862774,0.00628913,0.02574109,0.001751621],"domain_scores_gemma":[0.2747234,0.6188508,0.02583194,0.04204044,0.03242124,0.006132126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006241922,0.0003099859,0.01477868,0.03398922,0.004454515,0.0009537162,0.002488633,0.004583643,0.001112403,0.1448192,0.06153714,0.7303486],"study_design_scores_gemma":[0.0004518191,0.0005581504,0.006553066,0.1021051,0.002545873,0.0009185264,0.002203171,0.003912072,0.001340714,0.4563525,0.4227176,0.0003415121],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.008923906,0.3408277,0.1309098,0.4337174,0.007536637,0.002793051,0.007268228,0.000695557,0.0673277],"genre_scores_gemma":[0.1929011,0.330523,0.3526875,0.09436329,0.01522623,0.004736524,0.005785232,0.0006591596,0.003117982],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.2201585,"threshold_uncertainty_score":0.9616834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1443307571317479,"score_gpt":0.3959471921276504,"score_spread":0.2516164349959025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}