{"id":"W3088838079","doi":"10.3233/blc-200315","title":"Optimizing Sequence of PD-L1 Immune-Checkpoint Inhibitors and Radiation Therapy in Bladder Cancer","year":2020,"lang":"en","type":"article","venue":"Bladder Cancer","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Immunotherapy; Bladder cancer; Radiation therapy; Adjuvant; Immune system; Oncology; Combination therapy; Cancer; Immune checkpoint; Adjuvant therapy; Neoadjuvant therapy; Urology; Internal medicine; Cancer research; Immunology; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001036993,0.0002792723,0.0005182197,0.0001113213,0.00005129059,0.00002047144,0.00009337203,0.0001351681,0.0007872708],"category_scores_gemma":[0.00002967605,0.0002408403,0.0001237348,0.0004091172,0.0001274233,0.0001862934,0.00004398282,0.0002496911,0.000006408368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000203015,"about_ca_system_score_gemma":0.0004670227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004452098,"about_ca_topic_score_gemma":0.0001937944,"domain_scores_codex":[0.9983035,0.00005039499,0.0005235331,0.0004649298,0.0003209026,0.0003367361],"domain_scores_gemma":[0.9992612,0.0000343353,0.0001889703,0.0002192706,0.0001004844,0.0001957379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003645087,0.0005304948,0.2500048,0.0006029389,0.001643594,0.0001189799,0.02999816,0.001244026,0.4234552,0.00008085128,0.003037331,0.2856386],"study_design_scores_gemma":[0.02669496,0.002214589,0.323923,0.00128434,0.0006187002,0.00003342612,0.002074468,0.003265115,0.6161041,0.0001851531,0.02235081,0.001251314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9393926,0.0503922,0.00005183025,0.00742468,0.0003441805,0.001007612,0.0001129625,0.00006952065,0.001204385],"genre_scores_gemma":[0.9773642,0.01909485,0.0003505953,0.002275238,0.0004272519,0.0002630239,0.00001897129,0.00005521399,0.0001506099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2843873,"threshold_uncertainty_score":0.9821184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04154175308741016,"score_gpt":0.3114998640930575,"score_spread":0.2699581110056473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}