{"id":"W3089110905","doi":"10.1016/j.isci.2020.101598","title":"Phosphoproteomic Analysis of Xenopus laevis Reveals Expression and Phosphorylation of Hypoxia-Inducible PFKFB3 during Dehydration","year":2020,"lang":"en","type":"article","venue":"iScience","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Hebei Normal University; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Ontario","keywords":"Xenopus; Glycolysis; Dehydration; Phosphorylation; Biology; Biochemistry; Cell biology; Gluconeogenesis; Citric acid cycle; Metabolism; Metabolic pathway; Protein phosphorylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636804,0.00008419104,0.0001996346,0.00006668149,0.00005822814,0.00001133654,0.0001248657,0.00006440773,0.00001643611],"category_scores_gemma":[0.0001203445,0.00007924619,0.00006922583,0.000491407,0.00009381732,0.00001487449,0.00008187382,0.00003758436,5.783644e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005920316,"about_ca_system_score_gemma":0.00004228271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004991554,"about_ca_topic_score_gemma":0.000009047701,"domain_scores_codex":[0.9991357,0.00002603377,0.0002308147,0.0003222869,0.0001656425,0.0001195499],"domain_scores_gemma":[0.9994498,0.000006653699,0.0001904895,0.000204096,0.00007839094,0.00007060118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005153843,0.00001282602,0.002839564,0.00002663154,0.00002528146,1.02046e-7,0.0002743429,0.0006639359,0.9948106,0.00001236039,0.00006065231,0.001222175],"study_design_scores_gemma":[0.00023323,0.00006458694,0.0282156,0.00001375459,0.00008780746,7.191684e-7,0.00006035178,0.0006407858,0.9700677,0.0000152046,0.0005169309,0.00008334915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944463,0.003490586,0.001656793,0.00005792111,0.00009393219,0.0001279348,0.00001881989,0.000005033738,0.0001027142],"genre_scores_gemma":[0.9981743,0.0005787175,0.0009946438,0.00005474632,0.0000995041,0.000007138235,0.00001512033,0.000005613708,0.00007023706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02537604,"threshold_uncertainty_score":0.3231566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01247887979144172,"score_gpt":0.2437674460236482,"score_spread":0.2312885662322064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}