{"id":"W3089181101","doi":"10.1016/j.biopha.2020.110717","title":"Rosemary (Rosmarinus officinalis L.) extract inhibits prostate cancer cell proliferation and survival by targeting Akt and mTOR","year":2020,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Prostate Cancer Fight Foundation","keywords":"Prostate cancer; Protein kinase B; Androgen receptor; Rosmarinus; PI3K/AKT/mTOR pathway; Medicine; Cancer research; Prostate; Cancer; Internal medicine; Androgen; Oncology; Officinalis; Biology; Signal transduction; Hormone; Traditional medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007878865,0.0003448303,0.0003027915,0.0003939517,0.0001356445,0.0001551421,0.000155771,0.000159271,0.001471949],"category_scores_gemma":[0.00005417694,0.00008593998,0.0003872001,0.0001634155,0.00009262697,0.0001452862,0.000127908,0.000463215,0.0002605809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008877429,"about_ca_system_score_gemma":0.0001549055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004921849,"about_ca_topic_score_gemma":0.0009706352,"domain_scores_codex":[0.9999503,0.00001100832,0.000004594548,0.000007945439,0.0000128324,0.00001321236],"domain_scores_gemma":[0.9999762,0.000003164039,0.000008606888,0.000002508051,0.000004112039,0.000005561011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005170293,0.0002909061,0.0002688451,0.0003377276,0.00004032198,0.0000888904,0.00001823011,0.0001543516,0.9886556,0.0001071167,0.0002414301,0.009279657],"study_design_scores_gemma":[0.0001586973,0.004324171,0.01932887,0.00005792751,0.0001718869,0.0005648591,0.00005955064,0.00100611,0.961455,0.0001285991,0.01272741,0.00001686115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762305,0.01666027,0.001841895,0.0003909057,0.0000643611,0.00005396749,0.0006003152,0.000196261,0.003961501],"genre_scores_gemma":[0.9888024,0.006469586,0.001296628,0.0001190204,0.00003073883,0.00003067698,0.0005071478,0.0000134462,0.002730332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471949,"threshold_uncertainty_score":0.004924119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009965964281295179,"score_gpt":0.2542348617453328,"score_spread":0.2442688974640376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}