{"id":"W3089286588","doi":"10.5772/intechopen.93551","title":"Dengue Immunopathogenesis: A Crosstalk between Host and Viral Factors Leading to Disease: PART II - DENV Infection, Adaptive Immune Responses, and NS1 Pathogenesis","year":2020,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Consejo Nacional de Ciencia y Tecnología; International Development Research Centre","keywords":"Immunology; Dengue fever; Pathogenesis; Immune system; Cytokine storm; Dengue virus; Antibody; Biology; Acquired immune system; Antibody-dependent enhancement; Virology; Disease; Viral pathogenesis; Infectious disease (medical specialty); Medicine; Virus; Viral replication","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005083154,0.0009054206,0.0004871236,0.0005791282,0.0003969477,0.0009477951,0.0002657099,0.0005820559,0.001750423],"category_scores_gemma":[0.0001248198,0.000309952,0.0003788359,0.0002847147,0.000772476,0.0009521255,0.0009756409,0.001105906,0.0002203373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006928956,"about_ca_system_score_gemma":0.0005859963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004670822,"about_ca_topic_score_gemma":0.0004038956,"domain_scores_codex":[0.9997589,0.00007253615,0.00002218856,0.00003712512,0.00003831559,0.00007098023],"domain_scores_gemma":[0.9999055,0.00001734317,0.00002748948,0.000006227941,0.00001673516,0.0000267328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001198066,0.0007115414,0.02467098,0.003012107,0.0001454571,0.005789545,0.0008941869,0.001401661,0.82272,0.01694274,0.002912541,0.1196012],"study_design_scores_gemma":[0.000516816,0.006190869,0.5049585,0.001730347,0.0007150674,0.0304665,0.003942905,0.008497242,0.2920302,0.02944509,0.1213131,0.0001934044],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7056152,0.2539056,0.01584398,0.004290904,0.0007364263,0.0005827251,0.0004372279,0.0002526965,0.01833524],"genre_scores_gemma":[0.9039206,0.08502969,0.004612136,0.001031807,0.0004922188,0.000166215,0.0002442199,0.00001386889,0.004489325],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001750423,"threshold_uncertainty_score":0.00585568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02752570600315508,"score_gpt":0.265484165869408,"score_spread":0.2379584598662529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}