{"id":"W3089422717","doi":"10.1126/sciimmunol.abd2876","title":"IL-22–induced cell extrusion and IL-18–induced cell death prevent and cure rotavirus infection","year":2020,"lang":"en","type":"article","venue":"Science Immunology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Kenneth Rainin Foundation; National Institutes of Health; American Diabetes Association","keywords":"Rotavirus; Cell; Programmed cell death; Extrusion; Virology; Immunology; Biology; Microbiology; Virus; Medicine; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023775,0.0004266416,0.0004274766,0.0002608852,0.0001259951,0.0003258422,0.0001697921,0.0004235081,0.001565877],"category_scores_gemma":[0.0001726795,0.0001352484,0.0003178056,0.00008427339,0.0002465573,0.0002951619,0.000321261,0.0008326295,0.0003370354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001476867,"about_ca_system_score_gemma":0.0001721961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001177183,"about_ca_topic_score_gemma":0.0003706123,"domain_scores_codex":[0.9997458,0.00005565536,0.0000246997,0.00003302481,0.00005449957,0.00008641118],"domain_scores_gemma":[0.9998741,0.00001814942,0.00003912946,0.00001596355,0.00001457631,0.00003808283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002727713,0.0001444013,0.0003289413,0.00005570161,0.000007204382,0.00005535342,0.00001836201,0.00009056029,0.9949708,0.00009093553,0.00004922095,0.003915718],"study_design_scores_gemma":[0.00009571214,0.003187393,0.006729203,0.00001697971,0.0000223246,0.0005000051,0.00005048122,0.001034381,0.9831776,0.00008265693,0.005094911,0.000008350609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988679,0.003542101,0.005453053,0.0001523872,0.0001062729,0.0001237034,0.0001485145,0.0001009575,0.001694049],"genre_scores_gemma":[0.991476,0.00125195,0.004565863,0.0001133467,0.0000630554,0.0001053558,0.0002500937,0.0000175226,0.002156899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001565877,"threshold_uncertainty_score":0.005238354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05582412045446877,"score_gpt":0.3329804374693899,"score_spread":0.2771563170149211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}