{"id":"W3089422717","doi":"10.1126/sciimmunol.abd2876","title":"IL-22–induced cell extrusion and IL-18–induced cell death prevent and cure rotavirus infection","year":2020,"lang":"en","type":"article","venue":"Science Immunology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Kenneth Rainin Foundation; National Institutes of Health; American Diabetes Association","keywords":"Rotavirus; Cell; Programmed cell death; Extrusion; Virology; Immunology; Biology; Microbiology; Virus; Medicine; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005617295,0.0001777541,0.0003660016,0.0001767472,0.000269469,0.00003453645,0.0001648412,0.0001555852,0.0001245693],"category_scores_gemma":[0.0004547966,0.0001497047,0.00004609796,0.0003498369,0.0005169119,0.0002389801,0.0003833462,0.0005096848,0.00004901271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007575197,"about_ca_system_score_gemma":0.0001795263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003715824,"about_ca_topic_score_gemma":0.0000158088,"domain_scores_codex":[0.9980136,0.0001915156,0.0002854415,0.0006160183,0.0002166636,0.0006768259],"domain_scores_gemma":[0.9991776,0.00003172252,0.00009889622,0.0002393252,0.00009712805,0.0003553057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002280964,0.00008242927,0.02130058,0.00004403334,0.000007572642,0.00003267944,0.0001975027,8.363957e-7,0.9637488,0.00003213378,0.0001676084,0.01415774],"study_design_scores_gemma":[0.004653563,0.01462551,0.6273139,0.0001188303,0.00005838852,0.0006298598,0.0004063162,0.002273961,0.3423939,0.0004418067,0.006689586,0.0003944384],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943563,0.0005060413,0.0001117229,0.003253831,0.0002299405,0.0004397009,0.000005275495,0.0000512454,0.001045995],"genre_scores_gemma":[0.996921,0.001620119,0.00044611,0.0007550545,0.00008791849,0.00002324957,0.000006046871,0.00001223556,0.0001282586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6213549,"threshold_uncertainty_score":0.6104779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05582412045446877,"score_gpt":0.3329804374693899,"score_spread":0.2771563170149211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}