{"id":"W3089735440","doi":"10.1111/jnc.15203","title":"Impact of Wnt/β‐catenin signaling on ethanol‐induced changes in brain endothelial cell permeability","year":2020,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Health Sciences Centre; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba; Health Research","keywords":"Wnt signaling pathway; Ethanol; Endothelial stem cell; Catenin; Chemistry; Cell biology; Permeability (electromagnetism); Cell; Neuroscience; Signal transduction; Biology; Biochemistry; Membrane; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007764036,0.0002243301,0.0001997348,0.0001411598,0.00009323542,0.0002398087,0.0001069008,0.0001820619,0.001061427],"category_scores_gemma":[0.00008060787,0.0001159446,0.0002595504,0.0001514579,0.0001363461,0.0001978991,0.0001348311,0.0005138203,0.0001598703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003582597,"about_ca_system_score_gemma":0.0002377681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002702861,"about_ca_topic_score_gemma":0.00439262,"domain_scores_codex":[0.9999056,0.00001288525,0.00001300282,0.00001682263,0.0000191697,0.00003254696],"domain_scores_gemma":[0.9999406,0.000007841496,0.00001846471,0.000006505245,0.00001147572,0.00001513888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003043966,0.00004618663,0.0003700107,0.00004378483,0.00001044535,0.00004775953,0.00001874822,0.0000318256,0.9981757,0.00003957071,0.00002789426,0.0008835227],"study_design_scores_gemma":[0.00002003126,0.0004016344,0.01795139,0.000009518338,0.00003407764,0.00009500622,0.00007984959,0.0005060824,0.9798281,0.00002914203,0.001040492,0.000004668727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969606,0.001340082,0.0005064871,0.00007156689,0.00001564602,0.00001330051,0.000471858,0.00001877882,0.0006016],"genre_scores_gemma":[0.9945871,0.001499053,0.0006729265,0.00005266788,0.000003471545,0.00003055591,0.0006308596,0.000007191864,0.002516331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002702861,"threshold_uncertainty_score":0.005374193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02520263702063943,"score_gpt":0.2792181057862989,"score_spread":0.2540154687656594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}